CAJ | 학술논문

目的探讨支气管哮喘猝死的诱因以减少哮喘猝死发生。方法回顾性地复习并分析10例哮喘猝死患者的临床相关病史资料，结果10例患者中，9女1男，年龄21-53岁，平均年龄40.7岁。哮喘病史1-40年不等，平均约18.7年。发病季节和时间：1-2月发病3例，5-8月7例；有3例在夜间8-10p m时突发呼吸困难加重，7例在早晨至中午时突发；可能诱因：5例与进食（如鱼类、肉食等）有关，3例可能与感染加重有关，1例在登山活动中，1例在注射斯奇康后。10例患者中3例有哮喘家族史。本组病例中5例患者曾到呼吸专科进行过诊治，但依从性均差，其余5例从未到呼吸专科诊治。10例患者均未接受规范化治疗。5例在心肺复苏后急查血常规， WBC12.4—18.16x109/L者3例，嗜酸性粒细胞明显增高者2例。10例哮喘猝死患者均经心肺复苏，5例当即死亡，4例死于脑死亡及其它并发症，1例存留智力障碍。讨论：诱发和增加哮喘猝死的因素多种，如中青年女性、冬季与夏季、食物过敏、感染加重，家族史等，缺乏及时就医；加强对哮喘患者的防治教育和规范性治疗，及加强院前急救十分重要，可提高对支气管哮喘的防治水平，减少治哮喘猝死的发生。
목적탐토지기관효천졸사적유인이감소효천졸사발생。방법회고성지복습병분석10례효천졸사환자적림상상관병사자료，결과10례환자중，9녀1남，년령21-53세，평균년령40.7세。효천병사1-40년불등，평균약18.7년。발병계절화시간：1-2월발병3례，5-8월7례；유3례재야간8-10p m시돌발호흡곤난가중，7례재조신지중오시돌발；가능유인：5례여진식（여어류、육식등）유관，3례가능여감염가중유관，1례재등산활동중，1례재주사사기강후。10례환자중3례유효천가족사。본조병례중5례환자증도호흡전과진행과진치，단의종성균차，기여5례종미도호흡전과진치。10례환자균미접수규범화치료。5례재심폐복소후급사혈상규， WBC12.4—18.16x109/L자3례，기산성립세포명현증고자2례。10례효천졸사환자균경심폐복소，5례당즉사망，4례사우뇌사망급기타병발증，1례존류지력장애。토론：유발화증가효천졸사적인소다충，여중청년녀성、동계여하계、식물과민、감염가중，가족사등，결핍급시취의；가강대효천환자적방치교육화규범성치료，급가강원전급구십분중요，가제고대지기관효천적방치수평，감소치효천졸사적발생。
Objective To approach predisposition of Sudden death in asthma(SDA) and decrease SDA.Methods 10 cases history and related data of SDA were reviewed and analyzed.Results It was 10 cases, famale 9 and male 1, age 21-53 years old, mean 40.7 years. In which asthma history was 1—40years, mean 18,7 years.attack season and time:attack in January to February had 3 cases, attack in May to August 7 cases;attack in 8-10 pm had suddenly exacerbated dyspnea,7 cases attack in morning to noon; probable predispositions had that 5 cases were related to foods( fishes, meats ect ),3 cases were related to infections, 1 case in climbing, 1 case after getted a injection of SIQIKANG.. 3 cases had asthma family history in 10 cases. In this group , 5 cases had see respiratory doctor,but poor complications. Another 5 cases had no see a respiratory doctor. 10 cases all did not accept normalization treatment. Emergency routine blood test after cardiac pulmonary resuscitation in 5 cases showed WBC 12.4—18.16x109/L, 2 cases had distinct raised eosinophil. 5 cases died at once,4 cases died duo to Brain Death and other complications, 1 case survival but intellectual disorder. Conclusion The factors of sinduceded and increased SDA are many and varied, as young and middle-aged female, hard winter and summer, food caused allergy, exacerbated infections, asthma family history, and lack of medical service timely, ect. It was fully important that enhanced education of prevention and normalization cure to patients with asthma, and strengthen give first aid after admitted to hospital. It can raise the levers about prevention and cure; of bronchial asthma, and reduce.