CAJ | 학술논문

目的探讨卡维地洛治疗急性心肌梗死（AMI）患者左室功能的疗效。方法对于2005年1月～2009年7月在我院住院及出院后门诊随访的100例AMI患者随机分为卡维地洛组和美托洛尔组各50例，于入院后24小时内和治疗后1个月行超声心动图检查。比较2组间收缩功能和舒张功能的各种指标。结果治疗1个月后，在收缩功能方面，与美托洛尔组相比，卡维地洛组的改善更为明显（P<0.05），在舒张功能方面，两组的改善程度一样（P>0.05）。结论在治疗1个月后，卡维地洛和美托洛尔均显著改善左心室功能，但卡维地洛疗效更好。
목적탐토잡유지락치료급성심기경사（AMI）환자좌실공능적료효。방법대우2005년1월～2009년7월재아원주원급출원후문진수방적100례AMI환자수궤분위잡유지락조화미탁락이조각50례，우입원후24소시내화치료후1개월행초성심동도검사。비교2조간수축공능화서장공능적각충지표。결과치료1개월후，재수축공능방면，여미탁락이조상비，잡유지락조적개선경위명현（P<0.05），재서장공능방면，량조적개선정도일양（P>0.05）。결론재치료1개월후，잡유지락화미탁락이균현저개선좌심실공능，단잡유지락료효경호。
Object To explore the effect of treatment with carvedilol in patients with left ventricular dysfunction after acute myocardial infarction . Method From 2005.1 to 2009.7, 100 cases with acute myocardial infarction were randomly divided into two groups.carvedilol group (50 cases) and metoprolol group (50 cases) . The left ventricular systolic function and diastolic function of both group were recorded by echocardiography at the time both within 24 hours when the patient was hospitalized and one month after the end of treatment .Result The left ventricular systolic function of the carvedilol group improved more than the metoprolol group (P<0.05).There were no statistic difference of the improvement of the left ventricular diastolic function between the two groups(P﹥0.05).Conclusion Compared with metoprolol,the treatment with carvedilol in patients with left ventricular dysfunction after acute myocardial infarction have a better effect.