CAJ | 학술논문

目的探讨30例原发性胆汁反流性胃炎（Bile Reflux Gastritis, BRG）的内镜表现及相关影响因素。方法选择近一年有食道反流及一系列消化道症状且无手术史的患者进行胃镜检查，仔细观察胃底胃体黏膜糊颜色及附壁黏液颜色，根据胃液颜色及胆汁反流的程度进行分级，分别于胃体胃窦取黏膜做病理检查及幽门螺杆菌（Hp）检测。将BRG与同期非BRG的主要影响因素进行比较，用SPSS软件行卡方检验。结果本组30例BRG占同期内镜检查102例胃炎总人数的29.4%，其中男女比例1.5啰1，平均年龄35岁。按反流的轻重程度1级反流4例，2级反流17例，3级反流9例。结论 BRG形成的原因包括原发性和继发性，原发性BRG的发病机制与十二指肠球部溃疡或炎症有关，伴有十二指肠球部溃疡或炎症者，反流愈严重。因为胆汁酸能抑制HP的生长，胃内胆汁浓度与HP受抑制程度呈正相关。
목적탐토30례원발성담즙반류성위염（Bile Reflux Gastritis, BRG）적내경표현급상관영향인소。방법선택근일년유식도반류급일계렬소화도증상차무수술사적환자진행위경검사，자세관찰위저위체점막호안색급부벽점액안색，근거위액안색급담즙반류적정도진행분급，분별우위체위두취점막주병리검사급유문라간균（Hp）검측。장BRG여동기비BRG적주요영향인소진행비교，용SPSS연건행잡방검험。결과본조30례BRG점동기내경검사102례위염총인수적29.4%，기중남녀비례1.5라1，평균년령35세。안반류적경중정도1급반류4례，2급반류17례，3급반류9례。결론 BRG형성적원인포괄원발성화계발성，원발성BRG적발병궤제여십이지장구부궤양혹염증유관，반유십이지장구부궤양혹염증자，반류유엄중。인위담즙산능억제HP적생장，위내담즙농도여HP수억제정도정정상관。
Objective: To investigate the characteristics and the effects of endoscopy in 30 patients with primary bile reflux gastritis(BRG).Methods: Consecutive 30 patients with BRG verified by endoscopy and pathological examination in the patients with BRG of non-surgical operation were investigated. In addition, the associations among Helicobacter pylori (HP)infection in the antrum were analyzed.Results: Totally 102 patients with gastritis received endoscopy during the period, and 30 patients were diagnosed as BRG. The overall diagnostic was 29.4%. Ratio of male to female was 1.5:1. The average age diagnosed was 35 years old. The severity of the symptoms about patients with BRG was divided into three groups, and serious degree under endoscopic appearance was mild(4patients),moderate(17 patients)and severe(9 patients). Conclusions: The cause of BRG includes primary and secondary disease. The factors causing disease with BRG are relating with duodenal ulcer and duodenitis. The reflux symptoms are very serious in the patients with duodenal ulcer and duodenitis. The presence of antral HP infection is related to biliary density in the gastric antrum.