CAJ | 학술논문

目的检测新生儿窒息血清IgA、IgG、IgM、C3、超敏C-反应蛋白( hs-CRP)水平变化。方法分别选取窒息新生儿48例和16名正常新生儿，采用免疫比浊法检测血清IgA、IgG、IgM、C3和hs-CRP的水平。结果新生儿窒息组与正常对照组C3和IgG差异无统计学意义( P >0.05)， IgA 、IgM和hs-CRP两组差异有统计学意义( P <0.01)；轻度窒息组和重度窒息组患儿血清IgG、hs-CRP水平差异有统计学意义( P <0.01)，而血清IgA、IgM、C3水平差异无统计学意义( P >0.05)。结论新生儿窒息可使机体血清IgA、IgM水平下降，hs-CRP水平升高，对IgG影响不大；新生儿窒息程度与IgG、hs-CRP有一定关系。
목적검측신생인질식혈청IgA、IgG、IgM、C3、초민C-반응단백( hs-CRP)수평변화。방법분별선취질식신생인48례화16명정상신생인，채용면역비탁법검측혈청IgA、IgG、IgM、C3화hs-CRP적수평。결과신생인질식조여정상대조조C3화IgG차이무통계학의의( P >0.05)， IgA 、IgM화hs-CRP량조차이유통계학의의( P <0.01)；경도질식조화중도질식조환인혈청IgG、hs-CRP수평차이유통계학의의( P <0.01)，이혈청IgA、IgM、C3수평차이무통계학의의( P >0.05)。결론신생인질식가사궤체혈청IgA、IgM수평하강，hs-CRP수평승고，대IgG영향불대；신생인질식정도여IgG、hs-CRP유일정관계。
Objective: To detect the levels of serum IgA, IgG, IgM, C3 and hs-CRP in neonatal asphyxia .Methods:forty-eight cases of neonatal asphyxia and sixteen controls were concluded in this study. Immunoturbidimetric method was used to detect the serum levels of IgA, IgG, IgM, C3 and hs-CRP. Results: There was no statistical difference in C3 and IgG (P ﹥ 0.05), but IgM, IgA and hs-CRP were significantly different between the two groups (P < 0. 01).Serum IgG and hs-CRP were statistically significant between mild asphyxia group and severe asphyxia group ( P < 0. 01).There was no statistically difference in serum IgA, IgM and C3 ( P ﹥ 0.05). Conclusions: The levels of serum IgA and IgM decreased in neonatal asphyxia, while the level of hs-CRP increased. Neonatal asphyxia had little effect on serum IgG. The degree of neonatal asphyxia was related to the levels of serum IgG and hs-CRP.