CAJ | 학술논문

目的了解输注HIV感染者血液传播HIV的机率及其对艾滋病防治和研究的意义。方法对某医院26名接受HIV阳性供血员血液的患者进行随访及HIV和HCV筛查。结果1995年8月8日至1996年12月27日在该医院输注某HIV感染者全血的26名患者中8人已死亡，2人失访，在筛查的16名受血者中，15人抗-HIV阳性，14人抗-HCV阳性，接受输血后，HIV 和HCV传播率分别为93.8％和87.5％。1例受血者多次检查抗-HIV均为阴性，HIV-RNA阴性，但抗-HCV阳性，HCV-RNA阳性。被发现的HIV感染者均得到了救助、治疗和培训。结论在血传播为主的艾滋病疫区，对输注未经HIV及HCV检测血液的人群进行筛查有利于早期发现、治疗和救助HIV感染者，有利于避免HIV的二次传播。输注HIV感染者血液传播HIV概率很高，但确有个别人不受传染，其机制可能与基因类型有关，值得进一步研究。
목적료해수주HIV감염자혈액전파HIV적궤솔급기대애자병방치화연구적의의。방법대모의원26명접수HIV양성공혈원혈액적환자진행수방급HIV화HCV사사。결과1995년8월8일지1996년12월27일재해의원수주모HIV감염자전혈적26명환자중8인이사망，2인실방，재사사적16명수혈자중，15인항-HIV양성，14인항-HCV양성，접수수혈후，HIV 화HCV전파솔분별위93.8％화87.5％。1례수혈자다차검사항-HIV균위음성，HIV-RNA음성，단항-HCV양성，HCV-RNA양성。피발현적HIV감염자균득도료구조、치료화배훈。결론재혈전파위주적애자병역구，대수주미경HIV급HCV검측혈액적인군진행사사유리우조기발현、치료화구조HIV감염자，유리우피면HIV적이차전파。수주HIV감염자혈액전파HIV개솔흔고，단학유개별인불수전염，기궤제가능여기인류형유관，치득진일보연구。
Objective: To estimate the transmission rate of human immunodeficiency virus (HIV) by contaminated blood transfusion and provide information for the prevention of HIV transmission. Method:Twenty-six patients who had received blood transfusion from a donor infected with HIV were investigated and anti-HIV and anti-HCV were tested. Results:Eight of the patients died and 2 were missed. Among the other 16 patients, 15 were infected with HIV and 14 were anti-HCV positive. The transmission rates of HIV and HCV were 93.8%(15/16) and 87.5%(14/16) respectively. One patient’s anti-HIV and HIV-RNA were negative, but anti-HCV and HCV-RNA were positive. Free treatment、training and financial support were provided to all of the patients who infected with HIV. Conclusion: It is necessary to screen HIV-antibody for people who received blood transfusion without testing HIV during 1990’s in highly epidemic area of AIDS. The sceen help people who infected with HIV to get diagnosis、treatment and support earlier and to prevent the further spread of the diseases. There is very great probability to acquire HIV infection through contaminated blood transfusion, but there is exception. Some people may not susceptible to HIV infection. The mechanism needs further study.