CAJ | 학술논문

目的：分析幽门螺杆菌根除治疗对糖尿病性胃轻瘫临床疗效的影响。方法以2011年1月至2013年1月收治的100例糖尿病性胃轻瘫患者为研究对象，采用随机分配原则，将患者分为对照组和试验组各50例。对照组患者给予莫沙必利治疗，试验组患者在对照组治疗基础上增加幽门螺杆菌根除治疗，即增加阿莫西林、克拉霉素以及奥美拉唑治疗。比较两组患者的临床疗效及不良反应发生情况。结果试验组患者的临床总有效率（96.0%，48/50）明显高于对照组（80.0%，40/50），差异有统计学意义（P<0.05）；两组不良反应比较，差异无统计学意义（P>0.05）。结论对糖尿病性胃轻瘫患者实施幽门螺杆菌根除治疗效果显著，值得在临床推广和普及。
목적：분석유문라간균근제치료대당뇨병성위경탄림상료효적영향。방법이2011년1월지2013년1월수치적100례당뇨병성위경탄환자위연구대상，채용수궤분배원칙，장환자분위대조조화시험조각50례。대조조환자급여막사필리치료，시험조환자재대조조치료기출상증가유문라간균근제치료，즉증가아막서림、극랍매소이급오미랍서치료。비교량조환자적림상료효급불량반응발생정황。결과시험조환자적림상총유효솔（96.0%，48/50）명현고우대조조（80.0%，40/50），차이유통계학의의（P<0.05）；량조불량반응비교，차이무통계학의의（P>0.05）。결론대당뇨병성위경탄환자실시유문라간균근제치료효과현저，치득재림상추엄화보급。
Objective To analyze the curative effect of helicobacter pylori (Hp) eradication therapy in patients with dia-betic gastroparesis. Methods A total of 100 patients with diabetic gastroparesis ,who were treated in the hospital from January 2011 to January 2013,were collected and dividec into control group and experiment group based on the principle of random dis-tribution,50 cases in each group. The control group was treated with mosapride,while the experiment group was added with Hp eradication based on the treatment of control group ,which is added with amoxicillin ,clarithromycin and omeprazole for treatment. The clinical curative effect and adverse reactions between the two groups were observed and compared. Results The total effec-tive rate of experimental group (96.0%,48/50) was obviously higher than that of control group (80.0%,40/50) with statistically sig-nificant difference(P<0.05). There was no statistically significant difference on adverse reactions between the two groups(P>0.05). Conclusion The clinical research results show that the implementation of helicobacter pylori eradication in patients with diabetic gastroparesis treatment is with significant effect and worth promoting and popularizing.