中外健康文摘
中外健康文摘
중외건강문적
WORLD HEALTH DIGEST
2012年
33期
25-27
,共3页
肝炎病毒%乙型%酶联免疫吸附试验%血清学标志%转氨酶
肝炎病毒%乙型%酶聯免疫吸附試驗%血清學標誌%轉氨酶
간염병독%을형%매련면역흡부시험%혈청학표지%전안매
目的了解本地区人群乙型肝炎病毒(HBV)感染模式及其年龄分布,分析HBV感染者与非感染者血清转氨酶异常情况的差异.方法分别采用ELISA法和速率法,对5046例标本进行了乙型肝炎病毒感染血清标志物检测和血清转氨酶(ALT、AST).结果乙肝病毒标志物阳性血清(感染者)3070例,其中20岁以下452例,20-50(含20、50)岁2098例,50岁以上者520例.乙肝血清标志物感染模式有18种,其中HBsAb(+)占43.97%,HBsAg、HbeAb、HBcAb(+)占21.63%,HBsAg、HBeAg、HBcAb(+)占9.84%,为三种常见模式,而且这些模式在三个不同年龄组中构成比不同,用卡方检验比较,p值均<0.05,说明这几种模式分布存在年龄差异.3070例感染者血清转氨酶异常率为51.21%,其中ALT↑16.94%、AST↑7.43%、ALT↑AST↑26.84%；1976例非感染者血清转氨酶异常率为27.83%,其中ALT↑11.74%、AST↑4.15%、ALT↑AST↑11.94%,用卡方检验比较两组中各对应项比率间差异,p值均<0.05,说明感染组与非感染组血清转氨酶异常情况存在差异.结论 HBV感染模式多种多样,各模式在不同年龄段分布存在差异,常见主要模式差异更明显；HBV感染组与非感染组转氨酶异常情况存在明显差异,感染组异常比例高于非感染组.
目的瞭解本地區人群乙型肝炎病毒(HBV)感染模式及其年齡分佈,分析HBV感染者與非感染者血清轉氨酶異常情況的差異.方法分彆採用ELISA法和速率法,對5046例標本進行瞭乙型肝炎病毒感染血清標誌物檢測和血清轉氨酶(ALT、AST).結果乙肝病毒標誌物暘性血清(感染者)3070例,其中20歲以下452例,20-50(含20、50)歲2098例,50歲以上者520例.乙肝血清標誌物感染模式有18種,其中HBsAb(+)佔43.97%,HBsAg、HbeAb、HBcAb(+)佔21.63%,HBsAg、HBeAg、HBcAb(+)佔9.84%,為三種常見模式,而且這些模式在三箇不同年齡組中構成比不同,用卡方檢驗比較,p值均<0.05,說明這幾種模式分佈存在年齡差異.3070例感染者血清轉氨酶異常率為51.21%,其中ALT↑16.94%、AST↑7.43%、ALT↑AST↑26.84%；1976例非感染者血清轉氨酶異常率為27.83%,其中ALT↑11.74%、AST↑4.15%、ALT↑AST↑11.94%,用卡方檢驗比較兩組中各對應項比率間差異,p值均<0.05,說明感染組與非感染組血清轉氨酶異常情況存在差異.結論 HBV感染模式多種多樣,各模式在不同年齡段分佈存在差異,常見主要模式差異更明顯；HBV感染組與非感染組轉氨酶異常情況存在明顯差異,感染組異常比例高于非感染組.
목적료해본지구인군을형간염병독(HBV)감염모식급기년령분포,분석HBV감염자여비감염자혈청전안매이상정황적차이.방법분별채용ELISA법화속솔법,대5046례표본진행료을형간염병독감염혈청표지물검측화혈청전안매(ALT、AST).결과을간병독표지물양성혈청(감염자)3070례,기중20세이하452례,20-50(함20、50)세2098례,50세이상자520례.을간혈청표지물감염모식유18충,기중HBsAb(+)점43.97%,HBsAg、HbeAb、HBcAb(+)점21.63%,HBsAg、HBeAg、HBcAb(+)점9.84%,위삼충상견모식,이차저사모식재삼개불동년령조중구성비불동,용잡방검험비교,p치균<0.05,설명저궤충모식분포존재년령차이.3070례감염자혈청전안매이상솔위51.21%,기중ALT↑16.94%、AST↑7.43%、ALT↑AST↑26.84%；1976례비감염자혈청전안매이상솔위27.83%,기중ALT↑11.74%、AST↑4.15%、ALT↑AST↑11.94%,용잡방검험비교량조중각대응항비솔간차이,p치균<0.05,설명감염조여비감염조혈청전안매이상정황존재차이.결론 HBV감염모식다충다양,각모식재불동년령단분포존재차이,상견주요모식차이경명현；HBV감염조여비감염조전안매이상정황존재명현차이,감염조이상비례고우비감염조.
Objective: to know the region ofhepatitis B virus (hBV) infection pattern and agedistribution, analysis ofhBV infected and non-infected serum transaminase abnormalitiesdifferences.Methods:Using ELISAmethod and velocitymethod,5046 cases of specimens of serummarkers ofhepatitis B virus infection and serum transaminase (ALT, AST). Results:hepatitis B virusmarkers positive serum (infection) in 3070 cases, of which452wereUnder the age of 20,20-50(20,50), in 2098 cases,more than 50 years of age in 520 cases.Serologicalmarkers ofhepatitis B infection in any of 18modes, includinghBsAb (+)43.97%,hBsAg,hbeAb,hBcAb (+)21.63%,hBsAg,hBeAg,hBcAb (+) accounted for 9.84%, three kinds ofmodels, but thesemodels in threedifferent agegroups indifferent constituent ratios, chi-square test comparison, P<0.05, the severalmodes ofdistribution in the presence of agedifferences.3070 cases of abnormal serum aminotransferase ratio is 51.21%, where ALT=16.94%, AST=7.43%, ALT=AST=26.84%;1976cases of infection of abnormal serum aminotransferase ratio is 27.83%, where ALT=11.74%, AST=4.15%, ALT=AST=11.94%,Using the chi-square test were compared between the twogroups in the corresponding term ratiodifference, P<0.05, indicating infectiongroup and the non infectedgroup of abnormal serum aminotransferase isdifferent.Conclusion:hBV infection pattern varied, each pattern indifferent agedistributiond ifferences, commonmodedifference wasmore pronounced;hBV infectiongroup and non infectedgroup transaminase abnormalities exist obviousdifferences, infectiongroup anomaly ratio than non-infectedgroup.
