CAJ | 학술논문

目前，我国使用的甲肝疫苗，有灭活疫苗和减毒活疫苗两种，其中大部分地区纳入计划免疫的甲肝疫苗是减毒活疫苗，然而在欧美发达国家，采用的是甲肝灭活疫苗。通过调研相关文献，对甲肝灭活疫苗和减毒活疫苗进行比较，认为甲肝灭活疫苗在安全性，保护期，产生抗体时间，适用于应急接种，可与其他疫苗一起使用等方面优于减毒活疫苗，并且，甲肝减毒活疫苗的一针免疫程序效果欠佳，需要加强免疫。
목전，아국사용적갑간역묘，유멸활역묘화감독활역묘량충，기중대부분지구납입계화면역적갑간역묘시감독활역묘，연이재구미발체국가，채용적시갑간멸활역묘。통과조연상관문헌，대갑간멸활역묘화감독활역묘진행비교，인위갑간멸활역묘재안전성，보호기，산생항체시간，괄용우응급접충，가여기타역묘일기사용등방면우우감독활역묘，병차，갑간감독활역묘적일침면역정서효과흠가，수요가강면역。
At present, our use of hepatitis A vaccine, inactivated vaccine and live attenuated vaccines two kinds, which in most parts of the hepatitis A vaccine into the EPI is a live attenuated vaccine, however, developed countries in Europe and the United States, the use of inactivated hepatitis A vaccine. Through the research literature, the inactivated hepatitis A vaccine and live attenuated vaccine that inactivated vaccine safety, the protection period, time to produce antibodies, apply to emergency vaccination,which can be used in conjunction with other vaccines is superior to live attenuated vaccine, and one-dose schedule of live attenuated hepatitis A vaccine is ineffective, the need to strengthen immunity.