CAJ | 학술논문

目的比较肾上腺皮质激素,丙种球蛋白；血浆置换3种方法治疗重症肌无力危象的临床疗效。方法回顾性分析了50例重症肌无力危象患者的临床资料。其中(A组)18例进行肾上腺皮质激素治疗,(B组)20例进行丙种球蛋白治疗,(C组)12例进行血浆置换治疗,比较3组患者治疗呼吸机使用时间,入住ICU时间及肌力改善情况。结果3种方法治疗均有效,B组及C组在呼吸机使用时间、入住ICU时间更短、肌力改善情况更好。结论重症肌无力危象治疗激素治疗,丙种球蛋白治疗及血浆置换治疗均有效。丙种球蛋白治疗或者血浆置换治疗似乎更有效。
목적비교신상선피질격소,병충구단백；혈장치환3충방법치료중증기무력위상적림상료효。방법회고성분석료50례중증기무력위상환자적림상자료。기중(A조)18례진행신상선피질격소치료,(B조)20례진행병충구단백치료,(C조)12례진행혈장치환치료,비교3조환자치료호흡궤사용시간,입주ICU시간급기력개선정황。결과3충방법치료균유효,B조급C조재호흡궤사용시간、입주ICU시간경단、기력개선정황경호。결론중증기무력위상치료격소치료,병충구단백치료급혈장치환치료균유효。병충구단백치료혹자혈장치환치료사호경유효。
Objective: To compare the efficacy of adrenal cortex hormone, intravenous immunoglobulin and plasmapheresis on myasthenia gravis crisis. Methods The clinical data of 50 patients with myasthenia gravis crisis were analyzed retrospecticively, and patients were dived into Group A (18 cases under going adrenal cortex hormone) and Group B (20 cases under going intravenous immunoglobul -in) and Group C (12 cases under go plasmapheresis). We compared muscle force improvement mechanical ventilation and ICU days between the three groups. Results The 3 methods are all effective. Group B and Group C are shorter in mechanical ventilation and ICU days, the B and C Group is better in muscle force improvement. Conclusions: The 3 methods are used to myasthenia gravis crisis is all effective, especially the methods of intravenous immunoglobulin and plasmapheresis.