CAJ | 학술논문

目的探讨分析非典型川崎病(KD)的发病特点,以便早期诊断、早期治疗.方法回顾性分析2005年3月到2012年2月入住我院的103例小儿川崎病的临床资料,其中82例为典型KD,21例为非典型KD,分为典型组和非典型组两组,比较两组的临床症状、实验室检查结果(包括血分析、血沉、C-反应蛋白、血小板计数)的差异,并进行分析.结果非典型组中发热是其最常见的临床症状,其次是皮疹、口腔黏膜弥漫充血、皲裂,然后是指趾端硬肿脱皮,最少见的是眼结膜充血、颈淋巴结肿大.两组的临床症状相比差异具有统计学意义(p<0.05).两组大部分患者都有白细胞升高、血小板增加、C反应蛋白升高、血沉加快等.两组的实验室检查结果无明显差异,P>0.05,没有统计学意义.结论对于不符合典型川崎病诊断的疑诊病例,根据其临床症状和体征再结合实验室检查,排除其它如败血症、类风湿病等疾病后,即可诊断为非典型川崎病.
목적탐토분석비전형천기병(KD)적발병특점,이편조기진단、조기치료.방법회고성분석2005년3월도2012년2월입주아원적103례소인천기병적림상자료,기중82례위전형KD,21례위비전형KD,분위전형조화비전형조량조,비교량조적림상증상、실험실검사결과(포괄혈분석、혈침、C-반응단백、혈소판계수)적차이,병진행분석.결과비전형조중발열시기최상견적림상증상,기차시피진、구강점막미만충혈、군렬,연후시지지단경종탈피,최소견적시안결막충혈、경림파결종대.량조적림상증상상비차이구유통계학의의(p<0.05).량조대부분환자도유백세포승고、혈소판증가、C반응단백승고、혈침가쾌등.량조적실험실검사결과무명현차이,P>0.05,몰유통계학의의.결론대우불부합전형천기병진단적의진병례,근거기림상증상화체정재결합실험실검사,배제기타여패혈증、류풍습병등질병후,즉가진단위비전형천기병.
Objectives:To discuss and analyse atypical kawasaki disease's attack characteristics so as to make contribution to early diagnosis and early treatment.Methods:Made retrospective analysis to 103 of those kawasaki disease patients' clinical data,who have been treated at our hospital from March 2005 to February 2012.Divided them into typical group and atypical group,among them 82 cases belong to typical group and 21 cases belong to atypical group. Compared these two groups' clinical symptoms,laboratory test results'(including haemanalysis,blood sedimentation,C-reactive protein and platelet count) differences,and analysed them.Results:Fever is the most common clinical symptom in atypical group;rash,oral mucosa diffusion hyperaemia,rahagades are in the second place;after that is the toes hard swollen peeling;Eye conjunctival congestion and deradenoncus are the most rare.These two groups' clinical symptom comparison differences have statistics value(p<0.05).Most of the patients in these two groups occured interleukin increased,platelet increased,c-reactive protein elevated,blood sedimentation speed up symptoms,etc.There is no obvious difference between these two groups' laboratory test results,p>0.05,it has no statistics value. Conclusions:With regard to these suspected cases that inconformity with the typical kawasaki disease diagnosis,according to their clinical symptoms and signs,then combined with laboratory tests,after excluding other diseases such as ichorrhemia,juvenilerheumtoid disese,eventually we can diagnosed it as atypical kawasaki disease.