CAJ | 학술논문

目的探讨开颅术后烦躁不安的镇静镇痛治疗方案.方法回顾性分析捆绑制动、肌注氯丙嗪和静脉和静脉泵入曲马多合剂的三种治疗前、治疗中和治疗后的心电监护和颅内压监护情况及临床疗效.结果束带捆绑组的心率、平均动脉压和颅内压波动大，颅内再出血发生率高；肌注氯丙嗪组的呼吸频率、血氧饱和度(SpO2)有统计学意义(P<0.05)，肺部感染致死率为8.57%；曲马多合剂组的心率、呼吸、血氧饱和度(SpO2)、平均动脉压、和颅内压变化均无差异，颅内再出血发生率为2.12%.结论静脉泵入曲马多合剂一种比较理想的镇静镇痛方案，疗效确切值得推广.
목적탐토개로술후번조불안적진정진통치료방안.방법회고성분석곤방제동、기주록병진화정맥화정맥빙입곡마다합제적삼충치료전、치료중화치료후적심전감호화로내압감호정황급림상료효.결과속대곤방조적심솔、평균동맥압화로내압파동대，로내재출혈발생솔고；기주록병진조적호흡빈솔、혈양포화도(SpO2)유통계학의의(P<0.05)，폐부감염치사솔위8.57%；곡마다합제조적심솔、호흡、혈양포화도(SpO2)、평균동맥압、화로내압변화균무차이，로내재출혈발생솔위2.12%.결론정맥빙입곡마다합제일충비교이상적진정진통방안，료효학절치득추엄.
Objective To study the therapeutic regimen for controlling the dysphoria in postoperative patients of craniocerebral injury. Methods Retrospective analysis of electrocardio monitoring, intracranial pressure monitoring and clinical effect in patients who we applied braking ,intramuscularing Wintermin and injecting Tramadol misture via venous pump before the treatment,after the treatment and in the course of the treatment. Results Braking group: heart rate, mean arterial blood pressure and intracranial pressure fluctuated greatly, the rate of intracal rehaemorrhage was high. Intramuscularing Wintermin group: frequency of respiration and saturation of blood oxygen changed significantly (P<0.05), the fatality rate of pulmonary infection was 8.57%. Tramadol misture group: heart rate, frequency of respiration, saturation of blood oxygen,mean arterial blood pressure and intracranial pressure had no significant difference in the group. The rate of intracal rehaemorrhage was 2.12%.Conclusions Injecting Tramadol misture via venous pump is a relatively ideal therapeutic regimen of sedation and analgesia. The definite curative proposal is worth of spreading.