中外健康文摘
中外健康文摘
중외건강문적
WORLD HEALTH DIGEST
2012年
51期
12-12
,共1页
硝苯地平缓释片%厄贝沙坦%原发性高血压%疗效
硝苯地平緩釋片%阨貝沙坦%原髮性高血壓%療效
초분지평완석편%액패사탄%원발성고혈압%료효
Nifedipine%Irbesartan%Essential hypertension%Efficacy
目的观察硝苯地平缓释片联合厄贝沙坦治疗原发性高血压的临床疗效.方法对我院自2009年5月~2012年3月收治的125例原发性高血压患者的临床资料进行回顾性分析，所有患者均给予硝苯地平缓释片联合厄贝沙坦治疗，治疗周期为8周，观察本组患者的治疗效果及不良反应情况.结果(1)本组患者治疗2周时显效27例，有效69例，总有效率为76.8%；治疗4周时显效41例，有效62例，总有效率为82.4%；治疗8周时显效56例，有效65例，总有效率为96.8%.(2)本组患者治疗2周时收缩压较治疗前有明显改善(P<0.05)，治疗4周、8周后收缩压、舒张压均较治疗前有统计学差异(P<0.01).(3)本组患者出现头晕2例，心悸1例，均为一过性，调整药量后消失，未发现其他明显不良反应.结论硝苯地平缓释片联合厄贝沙坦治疗原发性高血压效果理想，且安全性较高，值得推广应用.
目的觀察硝苯地平緩釋片聯閤阨貝沙坦治療原髮性高血壓的臨床療效.方法對我院自2009年5月~2012年3月收治的125例原髮性高血壓患者的臨床資料進行迴顧性分析，所有患者均給予硝苯地平緩釋片聯閤阨貝沙坦治療，治療週期為8週，觀察本組患者的治療效果及不良反應情況.結果(1)本組患者治療2週時顯效27例，有效69例，總有效率為76.8%；治療4週時顯效41例，有效62例，總有效率為82.4%；治療8週時顯效56例，有效65例，總有效率為96.8%.(2)本組患者治療2週時收縮壓較治療前有明顯改善(P<0.05)，治療4週、8週後收縮壓、舒張壓均較治療前有統計學差異(P<0.01).(3)本組患者齣現頭暈2例，心悸1例，均為一過性，調整藥量後消失，未髮現其他明顯不良反應.結論硝苯地平緩釋片聯閤阨貝沙坦治療原髮性高血壓效果理想，且安全性較高，值得推廣應用.
목적관찰초분지평완석편연합액패사탄치료원발성고혈압적림상료효.방법대아원자2009년5월~2012년3월수치적125례원발성고혈압환자적림상자료진행회고성분석，소유환자균급여초분지평완석편연합액패사탄치료，치료주기위8주，관찰본조환자적치료효과급불량반응정황.결과(1)본조환자치료2주시현효27례，유효69례，총유효솔위76.8%；치료4주시현효41례，유효62례，총유효솔위82.4%；치료8주시현효56례，유효65례，총유효솔위96.8%.(2)본조환자치료2주시수축압교치료전유명현개선(P<0.05)，치료4주、8주후수축압、서장압균교치료전유통계학차이(P<0.01).(3)본조환자출현두훈2례，심계1례，균위일과성，조정약량후소실，미발현기타명현불량반응.결론초분지평완석편연합액패사탄치료원발성고혈압효과이상，차안전성교고，치득추엄응용.
Objective To observe the nifedipine sustained-release tablets and irbesartan clinical efficacy for the treatment of essential hypertension. Method Our hospital from May 2009 to March 2012, 125 cases admitted to the clinical data of patients with essential hypertension retrospective analysis, all patients were treated with nifedipine and irbesartan treatment, treatment period of eight weeks, the treatment effect observed in this group of patients, and adverse reactions. Results (1) 2 weeks of treatment in this group of patients, 27 cases markedly effective in 69 cases, total effective rate was 76.8%; 4 weeks of treatment, 41 cases markedly effective in 62 cases, total effective rate was 82.4%; 8 weeks of treatment 56 cases markedly effective in 65 cases, total effective rate of 96.8%. (2) the group of patients treated for 2 weeks, systolic blood pressure significantly improved (P<0.05) than before treatment treatment for 4 weeks, 8 weeks, systolic blood pressure, diastolic blood pressure than those before treatment a significant difference (P<0.01). (3) this group of patients dizziness, palpitations one cases are transient, adjust the dose disappear and found no other significant adverse reactions. Conclusion Nifedipine and irbesartan ideal for the treatment of essential hypertension in effect, higher security, should be widely applied.
