CAJ | 학술논문

目的探讨和研究头孢噻肟钠(凯福隆)治疗儿童细菌性脑膜炎的临床疗效.方法摘取我院近年来收治的124例细菌性脑膜炎患儿作为研究对象，按照随机分组的原则将之分为观察组和对照组各62例，其中观察组在积极常规治疗基础上用头孢噻肟钠进行治疗，对照组则在积极常规治疗基础上采用头孢曲松进行治疗，治疗结束后统计并对比两组患者的治疗结果.结果两组患儿的治疗总有效率均为100%，但观察组的显效率为93.55%(58/62)，对照组的显效率则为70.97%(44/62)，观察组明显优于对照组，差异具有统计学意义(P<0.05).两组患儿均无明显不良反应发生，在不良反应发生率方面无明显差异，不具有统计学意义(P>0.05).结论头孢噻肟钠治疗儿童细菌性脑膜炎的疗效显著，且安全性较高，值得在临床上加以推广和应用.
목적탐토화연구두포새우납(개복륭)치료인동세균성뇌막염적림상료효.방법적취아원근년래수치적124례세균성뇌막염환인작위연구대상，안조수궤분조적원칙장지분위관찰조화대조조각62례，기중관찰조재적겁상규치료기출상용두포새우납진행치료，대조조칙재적겁상규치료기출상채용두포곡송진행치료，치료결속후통계병대비량조환자적치료결과.결과량조환인적치료총유효솔균위100%，단관찰조적현효솔위93.55%(58/62)，대조조적현효솔칙위70.97%(44/62)，관찰조명현우우대조조，차이구유통계학의의(P<0.05).량조환인균무명현불량반응발생，재불량반응발생솔방면무명현차이，불구유통계학의의(P>0.05).결론두포새우납치료인동세균성뇌막염적료효현저，차안전성교고，치득재림상상가이추엄화응용.
Objective :To investigate the clinical efficacy for the treatment of bacterialmeningitis in children and research cefotaxime sodium (claforan). Method :Admitted to our hospital in recent years clinical data of 124 cases of bacterial meningitis in children as research subjects, divided into observation group and the control group, 62 cases in each in accordance with the principle of randomization observation group actively conventional treatment cefotaxime sodium for treatment, control group actively conventional treatment using ceftriaxone treatment, statistics and compare the treatment outcomes of patients after treatment. Results:Of the treatment of the two groups of children with total efficiency were 100%, but the effective rate is 93.55% of the observation group (58/62), the remarkable efficiency of the control group compared with 70.97% (44/62), the observation group was significantly better than control group, the difference was statistically significant (P <0.05). The two groups of children had no significant adverse events, no significant difference in the incidence of adverse reactions was not statistically significant (P> 0.05). Conclusion :Cefotaxime sodium in the treatment of bacterial meningitis in children a significant effect, and security is high, it is worth to be promoted and applied in the clinical.