CAJ | 학술논문

目的：观察奥曲肽治疗肝硬化所致上消化道出血的临床疗效。方法将86例肝硬化并上消化道出血患者随机分为两组，两组患者均给予综合支持治疗，对照组43例患者给予垂体后叶素治疗，治疗组43例患者给予奥曲肽治疗，观察两组患者的临床疗效及止血效果。结果治疗组疗效明显优于对照组，止血时间明显短于对照组，48h再出血率及并发症发生率明显低于对照组（P＜0.05）。结论奥曲肽治疗肝硬化所致上消化道出血临床效果显著，止血迅速且不良反应少，是目前治疗肝硬化上消化道出血理想药物。
목적：관찰오곡태치료간경화소치상소화도출혈적림상료효。방법장86례간경화병상소화도출혈환자수궤분위량조，량조환자균급여종합지지치료，대조조43례환자급여수체후협소치료，치료조43례환자급여오곡태치료，관찰량조환자적림상료효급지혈효과。결과치료조료효명현우우대조조，지혈시간명현단우대조조，48h재출혈솔급병발증발생솔명현저우대조조（P＜0.05）。결론오곡태치료간경화소치상소화도출혈림상효과현저，지혈신속차불량반응소，시목전치료간경화상소화도출혈이상약물。
Objective Observation of octreotide in the treatment of liver cirrhosis caused by upper gastrointestinal bleeding. Method 86 cases of liver cirrhosis with upper gastrointestinal hemorrhage were randomly divided into two groups,Two groups of patients were given comprehensive support treatment, On the basis of ,The control group of 43 patients with pituitrin treatment, 43 patients in treatment group were treated with octreotide, To observe the clinical efficacy of two groups of patients and hemostatic effect. Result Curative effect in treatment group was better than control group, the bleeding time significantly shorter than the control group, 48 h and bleeding rate and complication rates significantly lower than the control group (P < 0.05).Conclusion Mr Qu peptide treatment of liver cirrhosis upper gastrointestinal bleeding caused by clinical effect is remarkable, stop bleeding quickly and less adverse reaction, Is the ideal drug treatment of liver cirrhosis upper gastrointestinal bleeding.