CAJ | 학술논문

目的：探讨雄激素联合环孢菌素A治疗再生障碍性贫血的临床疗效。方法：选取我院收治的50例再生障碍性贫血患者作为研究对象，本组患者均采用雄激素联合环孢菌素A进行治疗，对其临床特征及治疗效果进行回顾性分析。结果：本组患者的治疗总有效率为52.0%；其中S A A的总有效率为20.0%， CAA的总有效率为60.0%。病程小于6个月的CAA患者，治疗总有效率显著高于病程在0.5～2年之间及大于2年者，P<0.05，差异均具有统计学意义。治疗后，网织红细胞计数首先明显升高，然后是血红蛋白计数增多，其后为白细胞计数、中性粒细胞计数增多，最后为血小板计数升高。结论：再生障碍性贫血患者应用雄激素联合环孢菌素A进行治疗，具有确切的治疗效果，是治疗再生障碍性贫血的理想方法。
목적：탐토웅격소연합배포균소A치료재생장애성빈혈적림상료효。방법：선취아원수치적50례재생장애성빈혈환자작위연구대상，본조환자균채용웅격소연합배포균소A진행치료，대기림상특정급치료효과진행회고성분석。결과：본조환자적치료총유효솔위52.0%；기중S A A적총유효솔위20.0%， CAA적총유효솔위60.0%。병정소우6개월적CAA환자，치료총유효솔현저고우병정재0.5～2년지간급대우2년자，P<0.05，차이균구유통계학의의。치료후，망직홍세포계수수선명현승고，연후시혈홍단백계수증다，기후위백세포계수、중성립세포계수증다，최후위혈소판계수승고。결론：재생장애성빈혈환자응용웅격소연합배포균소A진행치료，구유학절적치료효과，시치료재생장애성빈혈적이상방법。
Objective: to study the androgen joint ring spore fungus element A clinical curative effect for the treatment of aplastic anemia. Selection methods: our hospital as the research object of 50 cases of aplastic anemia patients, the patients adopt androgen joint ring spore fungus element A treatment, the clinical characteristics and treatment effects were retrospectively analyzed. Results: the treatment of patients with the total effective rate was 52.0%; One of the SAA total effective rate was 20.0%, the CAA total effective rate was 60.0%. Duration less than 6 months of CAA patients, total effective rate is significantly higher than the course between 0.5 ~ 2 years and more than 2 years, P < 0.05, differences were statistical y significant. After treatment, reticulocyte count significantly increased first, and then the hemoglobin count increased, then for increased WBC count, neutrophil count, final y to increase the platelet count. Conclusion: patients with aplastic anemia application androgen joint ring spore fungus element A treatment, has A definite therapeutic effect, is the ideal method for the treatment of aplastic anemia.