CAJ | 학술논문

目的：探讨体外冲击波联合中草药刺激兔骨不连间隙骨痂形成的机制。方法：选用标准实验新西兰大白兔66只，无菌条件下制作兔桡骨骨不连模型，随机分为A、B、C、D四组。A组为体外冲击波联合接骨仙桃草治疗组；B组为单纯接骨仙桃草治疗组；C组为单纯体外冲击波治疗组；D组为完全对照组，于治疗前后观察和比较各组骨痂生成量，并作统计学分析。结果：冲击波及治疗前后各时间段骨不连区骨痂生成量：A组及C组各时间点与治疗前相比较有统计学意义（P<0.05）；A组与对照组各时间段比较有显著性差异(P<0.01)； A组与C组第2、4、6、8周比较有差异(P<0.05)；B组与对照组各时间段无统计学意义（p>0.05）。结论：仙桃草可以在体外冲击波治疗骨不连后的早期就能起到促进骨折愈合的作用，为非手术治疗骨不连提供了一种良好的协同方法。
목적：탐토체외충격파연합중초약자격토골불련간극골가형성적궤제。방법：선용표준실험신서란대백토66지，무균조건하제작토뇨골골불련모형，수궤분위A、B、C、D사조。A조위체외충격파연합접골선도초치료조；B조위단순접골선도초치료조；C조위단순체외충격파치료조；D조위완전대조조，우치료전후관찰화비교각조골가생성량，병작통계학분석。결과：충격파급치료전후각시간단골불련구골가생성량：A조급C조각시간점여치료전상비교유통계학의의（P<0.05）；A조여대조조각시간단비교유현저성차이(P<0.01)； A조여C조제2、4、6、8주비교유차이(P<0.05)；B조여대조조각시간단무통계학의의（p>0.05）。결론：선도초가이재체외충격파치료골불련후적조기취능기도촉진골절유합적작용，위비수술치료골불련제공료일충량호적협동방법。
Objective:To explore the cal us formation mechanism of extracorporeal shock wave combine with Chinese herbal medicine on rabbit bone nonunion clearance.METHODS: 66 standard experiment New Zealand white rabbits were chosen, the rabbit models of radial bone nonunion were made under aseptic conditions that were randomly divided into A, B, C, D four groups. Group A was treated by extracorporeal shock wave combine with Chinese herbal medicine; Group B was treated by bone Veronica peregrina L;Group C was treated by extracorporeal shock wave; Group D was control.Observe and compare the generation bone cal us of each group before and after the treatment, and statistical analysis. RESULTS:The generation bone cal us of bone nonunion treated by extracorporeal shock wave and before and after the treatment each time point: Group A and group C each time point compared with before treatment was statistical y significant.(P<0.05);Group A each time point compared with control group was statistical y significant (P<0.01); Group A compared with group C was statistical y significant in 2, 4, 6, 8 weeks(P<0.05);Group B each time point compared with control group without statistical significance.(p>0.05).CONCLUSION: Veronica peregrina L can accelerate fracture healing after bone nonunion treated by extracorporeal shock wave in the early time that provides a good method for the on-surgical treatment of bone nonunion.