CAJ | 학술논문

目的：探讨PET-CT显像对卵巢恶性肿瘤淋巴结转移的诊断价值。方法对52例卵巢恶性肿瘤患者（初治39例、复发13例）于手术前采用PET-CT检测预测腹膜后淋巴结转移状况及位置。初治患者行卵巢癌肿瘤细胞减灭术同时行腹膜后淋巴结清扫术，复发患者行病灶及区域淋巴结清扫术。将术前PET-CT检测结果与术后淋巴结病理检查结果进行对照，计算PET-CT检测诊断卵巢恶性肿瘤淋巴结转移的敏感性、特异性、准确性、阳性预测值和阴性预测值。结果 PET-CT显像诊断腹膜后淋巴结转移的敏感性、特异性、准确性、阳性预测值和阴性预测值分别为96．30％（26/27）、92．00％（23/25）、94．23％（49/52）、92．86％（26/28）和95．83％（23/24）；诊断腹主动脉旁淋巴结转移的敏感性、特异性、准确性、阳性预测值和阴性预测值分别为96．30％（26/27）、100．％（25/25）、98．08％（51/52）、100％（26/26）和96．15％（25/26）；诊断盆腔淋巴结转移的敏感性、特异性、准确性、阳性预测值和阴性预测值分别为90．91％（10/11）、95．12％（39/41）、94．23％（49/52）、83．33％（10/12）和97．50％（39/40）。结论 PET-CT在卵巢恶性肿瘤淋巴结转移诊断方面有较高的临床价值。
목적：탐토PET-CT현상대란소악성종류림파결전이적진단개치。방법대52례란소악성종류환자（초치39례、복발13례）우수술전채용PET-CT검측예측복막후림파결전이상황급위치。초치환자행란소암종류세포감멸술동시행복막후림파결청소술，복발환자행병조급구역림파결청소술。장술전PET-CT검측결과여술후림파결병리검사결과진행대조，계산PET-CT검측진단란소악성종류림파결전이적민감성、특이성、준학성、양성예측치화음성예측치。결과 PET-CT현상진단복막후림파결전이적민감성、특이성、준학성、양성예측치화음성예측치분별위96．30％（26/27）、92．00％（23/25）、94．23％（49/52）、92．86％（26/28）화95．83％（23/24）；진단복주동맥방림파결전이적민감성、특이성、준학성、양성예측치화음성예측치분별위96．30％（26/27）、100．％（25/25）、98．08％（51/52）、100％（26/26）화96．15％（25/26）；진단분강림파결전이적민감성、특이성、준학성、양성예측치화음성예측치분별위90．91％（10/11）、95．12％（39/41）、94．23％（49/52）、83．33％（10/12）화97．50％（39/40）。결론 PET-CT재란소악성종류림파결전이진단방면유교고적림상개치。
Objective To investigate the diagnostic value of positron emission tomography and computed tomography ( PET-CT) in lymph node metastasis of malignant ovarian tumor .Methods Totally fifty-two patients with malignant ovari-an cancer were collected , including 39 primary and 13 reoccurred patients .PET-CT was performed to forecast the status and position of retroperitoneal lymph node before surgery .Cytoreductive surgery combined with retroperitoneal lymph node dissection was done on the primary patients , lesions and regional lymph node dissection was done on the reoccurred pa-tients.The results of PET-CT detection and pathological examination of lymph node before and after surgery were com -pared, and then the sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value ( NPV) of PET-CT detection in lymph node metastasis of malignant ovarian tumor were calculated .Results The sensitivi-ty, specificity, accuracy, PPV, and NPV of PET-CT in diagnosing retroperitoneal lymph node metastasis were 96.30%(26/27), 92.00%(23/25), 94.23%(49/52), 92.86%(26/28) and 95.83%(23/24), respectively.The sensitivi-ty, specificity, accuracy, PPV, and NPV of PET-CT in diagnosing para-aortic lymph node metastasis were 96.30%(26/27), 100.00%(25/25), 98.08%(51/52), 100.00%(26/26) and 96.15%(25/26), respectively.The sensitivity, specificity, accuracy, PPV, and NPV of PET-CT in diagnosing pelvic lymph node metastasis were 90.91% (10/11), 95.12%(39/41), 94.23%(49/52), 83.33%(10/12) and 97.50%(39/40), respectively.Conclusions PET-CT detection of lymph node metastasis in malignant ovarian tumor shows an accurate diagnostic value .