中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2014年
13期
195-196,198
,共3页
内皮细胞微粒%脓毒症%炎症%凝血%内皮功能障碍
內皮細胞微粒%膿毒癥%炎癥%凝血%內皮功能障礙
내피세포미립%농독증%염증%응혈%내피공능장애
EMPs%Sepsis%Inflammation%Coagulation%Endothelial dysfunction
内皮细胞在凋亡或激活条件下可以释放一种直径为0.05~1的囊泡状物质，我们称其为内皮细胞微粒。在脓毒血症中我们发内皮细胞微粒水平明显升高，这说明内皮细胞微粒与脓毒血症之间存在着一定关系。内皮细胞微粒通过自身表达的物质及刺激其他细胞表达的物质而在炎症、凝血、血管功能改变中产生重要作用。该研究就内皮细胞微粒的形成及与脓毒血症的关系做一概述。
內皮細胞在凋亡或激活條件下可以釋放一種直徑為0.05~1的囊泡狀物質，我們稱其為內皮細胞微粒。在膿毒血癥中我們髮內皮細胞微粒水平明顯升高，這說明內皮細胞微粒與膿毒血癥之間存在著一定關繫。內皮細胞微粒通過自身錶達的物質及刺激其他細胞錶達的物質而在炎癥、凝血、血管功能改變中產生重要作用。該研究就內皮細胞微粒的形成及與膿毒血癥的關繫做一概述。
내피세포재조망혹격활조건하가이석방일충직경위0.05~1적낭포상물질，아문칭기위내피세포미립。재농독혈증중아문발내피세포미립수평명현승고，저설명내피세포미립여농독혈증지간존재착일정관계。내피세포미립통과자신표체적물질급자격기타세포표체적물질이재염증、응혈、혈관공능개변중산생중요작용。해연구취내피세포미립적형성급여농독혈증적관계주일개술。
Under apoptosis or activated conditions, the endothelial cells can shed a diameter of 0.05-1vesicle-like substances, named endothelial microparticles (EMPs). It has been documented that the level of EMPs significantly increased in sepsis, which indicated that there is a certain relationship between the EMPs and sepsis. The substances expressed by EMPs and other cells stimulated by EMPs play an important role in inflammation, coagulation, vascular functional changes. This review was written to give an outline about the formation of EMPs and the relationship between EMPs and sepsis.
