中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2014年
13期
117-118
,共2页
腔镜胆囊切除术%急性炎症%应激反应
腔鏡膽囊切除術%急性炎癥%應激反應
강경담낭절제술%급성염증%응격반응
Laparoscopic cholecystectomy%Acute inflammation%Stress response
目的：探讨腹腔镜胆囊切除术对病人机体急性炎症应激反应的影响。方法选取该院行腹腔镜胆囊切除术的病人75例作为研究组，选取同期行开腹胆囊切除术手术的病人22例作为对照组，比较两组病人术后急性验证应激反应情况。结果术后1、5、6、7d发生全身炎症反应的病人研究组分别为52.0%、13.33%、8.0%、0%，对照组分别为77.27%、27.27%、18.18%、13.64%，研究组全身炎症反应病人明显少于对照组，差异有统计学意义（P<0.05），术后2~4 d两组存在全身炎症反应的病人，差异无统计学意义（P>0.05）；两组病人术后12、24、36 h CRP表达水平均较术前有显著升高（P<0.01），术后12 h、24 h CRP表达水平研究组分别为（25.8±10.5）mg/L、（54.7±20.8）mg/L，对照组分别为（40.9±12.9）mg/L、（66.9±21.4）mg/L，研究组明显低于对照组，差异有统计学意义（P<0.05），术后36 h两组差异无统计学意义。结论腹腔镜胆囊切除术较开腹手术炎症反应更轻，术前必须加强对长时间气腹缺血造成的氧化应激的重视，积极采取相应的措施，加快病人恢复。
目的：探討腹腔鏡膽囊切除術對病人機體急性炎癥應激反應的影響。方法選取該院行腹腔鏡膽囊切除術的病人75例作為研究組，選取同期行開腹膽囊切除術手術的病人22例作為對照組，比較兩組病人術後急性驗證應激反應情況。結果術後1、5、6、7d髮生全身炎癥反應的病人研究組分彆為52.0%、13.33%、8.0%、0%，對照組分彆為77.27%、27.27%、18.18%、13.64%，研究組全身炎癥反應病人明顯少于對照組，差異有統計學意義（P<0.05），術後2~4 d兩組存在全身炎癥反應的病人，差異無統計學意義（P>0.05）；兩組病人術後12、24、36 h CRP錶達水平均較術前有顯著升高（P<0.01），術後12 h、24 h CRP錶達水平研究組分彆為（25.8±10.5）mg/L、（54.7±20.8）mg/L，對照組分彆為（40.9±12.9）mg/L、（66.9±21.4）mg/L，研究組明顯低于對照組，差異有統計學意義（P<0.05），術後36 h兩組差異無統計學意義。結論腹腔鏡膽囊切除術較開腹手術炎癥反應更輕，術前必鬚加彊對長時間氣腹缺血造成的氧化應激的重視，積極採取相應的措施，加快病人恢複。
목적：탐토복강경담낭절제술대병인궤체급성염증응격반응적영향。방법선취해원행복강경담낭절제술적병인75례작위연구조，선취동기행개복담낭절제술수술적병인22례작위대조조，비교량조병인술후급성험증응격반응정황。결과술후1、5、6、7d발생전신염증반응적병인연구조분별위52.0%、13.33%、8.0%、0%，대조조분별위77.27%、27.27%、18.18%、13.64%，연구조전신염증반응병인명현소우대조조，차이유통계학의의（P<0.05），술후2~4 d량조존재전신염증반응적병인，차이무통계학의의（P>0.05）；량조병인술후12、24、36 h CRP표체수평균교술전유현저승고（P<0.01），술후12 h、24 h CRP표체수평연구조분별위（25.8±10.5）mg/L、（54.7±20.8）mg/L，대조조분별위（40.9±12.9）mg/L、（66.9±21.4）mg/L，연구조명현저우대조조，차이유통계학의의（P<0.05），술후36 h량조차이무통계학의의。결론복강경담낭절제술교개복수술염증반응경경，술전필수가강대장시간기복결혈조성적양화응격적중시，적겁채취상응적조시，가쾌병인회복。
Objective To investigate the effect of laparoscopic cholecystectomy on emergency response to acute inflammation pa-tient body. Methods 75 patients treated by laparoscopic cholecystectomy from September,2010 to September,2013 in our hospital as study group, select the same period underwent open cholecystectomy operation 22 cases of patients as the control group, com-pared two groups of patients after acute verification emergency response. Results The patients in the study group after 1, 5, 6, 7d incidence of systemic inflammatory response were 52%, 13.33%, 8%, 0%, control group were 77.27%, 27.27%, 18.18%, 13.64%, systemic inflammatory response of patients in study group were significantly less than the control group(P<0.05), no significant dif-ference between the two groups in 2~4d after operation systemic inflammatory response of patients (P>0.05);two groups of patients after 12 h, 24 h, 36 h CRP expression levels were significantly increased(P<0.01), after 12 h, 24 h CRP expression group research levels were (25.8 ±10.5) mg/L, (54.7 ±20.8) mg/L, the control group not (40.9 ±12.9) mg/L, (66.9 ±21.4) mg/L, the study group was significantly lower than that of the control group (P<0.05), postoperative 36h was not significant difference between the two groups. Conclusion laparoscopic cholecystectomy compared with open operation inflammation lighter, preoperative must strengthen to ox-idative stress caused by long time pneumoperitoneum ischemia attention, active measures, to speed up the patient's recovery.
