中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2014年
13期
46-47
,共2页
血清降钙素原%小儿重症胰腺炎%抗生素%临床价值
血清降鈣素原%小兒重癥胰腺炎%抗生素%臨床價值
혈청강개소원%소인중증이선염%항생소%림상개치
Serum procalcitonin%Severe pancreatitis in children%Antibiotics%Clinical value
目的：对血清降钙素原水平在小儿重症胰腺炎抗生素使用中的临床价值进行评价分析，为今后的临床抗生素使用工作提供可靠的参考依据。方法抽取在2011年9月—2013年9月间该院收治的小儿急性胰腺炎并发感染者86例，将其按照用药治疗方法分成对照组和观察组，对照组患者接受常规治疗，观察组患者接受血清降钙素原水平监测，依照监测结果合理选择抗生素治疗，而后对这两组患者的治疗效果进行对比分析。结果观察组住院时间显著短于对照组，抗生素疗程超过10 d者所占比例显著少于对照组，抗生素应用率、二重感染发生率以及药物不良反应发生率均显著低于对照组（P<0.05）。结论降钙素原水平检测在小儿急性胰腺炎并发感染临床诊断和治疗中具有重要意义，在治疗中准确监测患儿体内降钙素原水平可大幅提高治疗效果。
目的：對血清降鈣素原水平在小兒重癥胰腺炎抗生素使用中的臨床價值進行評價分析，為今後的臨床抗生素使用工作提供可靠的參攷依據。方法抽取在2011年9月—2013年9月間該院收治的小兒急性胰腺炎併髮感染者86例，將其按照用藥治療方法分成對照組和觀察組，對照組患者接受常規治療，觀察組患者接受血清降鈣素原水平鑑測，依照鑑測結果閤理選擇抗生素治療，而後對這兩組患者的治療效果進行對比分析。結果觀察組住院時間顯著短于對照組，抗生素療程超過10 d者所佔比例顯著少于對照組，抗生素應用率、二重感染髮生率以及藥物不良反應髮生率均顯著低于對照組（P<0.05）。結論降鈣素原水平檢測在小兒急性胰腺炎併髮感染臨床診斷和治療中具有重要意義，在治療中準確鑑測患兒體內降鈣素原水平可大幅提高治療效果。
목적：대혈청강개소원수평재소인중증이선염항생소사용중적림상개치진행평개분석，위금후적림상항생소사용공작제공가고적삼고의거。방법추취재2011년9월—2013년9월간해원수치적소인급성이선염병발감염자86례，장기안조용약치료방법분성대조조화관찰조，대조조환자접수상규치료，관찰조환자접수혈청강개소원수평감측，의조감측결과합리선택항생소치료，이후대저량조환자적치료효과진행대비분석。결과관찰조주원시간현저단우대조조，항생소료정초과10 d자소점비례현저소우대조조，항생소응용솔、이중감염발생솔이급약물불량반응발생솔균현저저우대조조（P<0.05）。결론강개소원수평검측재소인급성이선염병발감염림상진단화치료중구유중요의의，재치료중준학감측환인체내강개소원수평가대폭제고치료효과。
Objective To evaluate the clinical value of serum calcitonin levels in the use of antibiotics in children with severe a-cute pancreatitis so as to provide a reliable reference for clinical antibiotic use. Methods 86 cases of children with acute pancre-atitis complicated by infection admitted in our hospital from September, 2011 to September, 2013 were selected and divided into the control group and the observation group in accordance with the drug therapy. The control group was given conventional treat-ment, and the observation group was given the monitoring of serum procalcitonin level, and rational antibiotics therapy according to the monitoring results. The treatment effect of two groups of patients was compared and analyzed. Results The length of stay of the observation group was significantly shorter than that of the control group; the proportion of patients who used antibiotics over 10 days was obviously less than that of the control group; the utility ratio of antibiotics, the incidences of double infection and drug adverse reactions were much lower than those of the control group (P<0.05). Conclusion The monitoring of procalcitonin levels has significance in the clinical diagnosis and treatment of children with acute pancreatitis complicated by infection, the accurate moni-toring of procalcitonin levels can greatly improve the therapeutic effect during the treatment.
