现代医药卫生
現代醫藥衛生
현대의약위생
MODERN MEDICINE HEALTH
2014年
10期
1465-1466
,共2页
磷脂酰胆碱类%肝炎%治疗结果%非酒精性脂肪性肝炎%舒血宁注射液
燐脂酰膽堿類%肝炎%治療結果%非酒精性脂肪性肝炎%舒血寧註射液
린지선담감류%간염%치료결과%비주정성지방성간염%서혈저주사액
Phosphatidylcholines%Hepatitis%Treatment outcome%Non-alcoholic steatohepatitis%Shu xue ning injection
目的：观察多烯磷脂酰胆碱联合舒血宁注射液治疗非酒精性脂肪性肝炎（NASH）的疗效。方法将2012年1月至2013年7月收治的60例NASH患者随机分为治疗组和对照组，各30例；治疗组患者静脉滴注多烯磷脂酰胆碱和舒血宁注射液，对照组患者仅静脉滴注多烯磷脂酰胆碱；比较两组患者用药前后的肝功能变化及疗效。结果治疗组患者肝功能指标治疗后较治疗前有显著改善，且优于对照组治疗后，差异均有统计学意义（P<0.05）；治疗组总有效率（86.67%，26/30）高于对照组（3.33%，16/30），差异有统计学意义（χ2=7.94，P<0.01）。结论多烯磷脂酰胆碱联合舒血宁注射液治疗NASH有显著疗效，值得临床借鉴。
目的：觀察多烯燐脂酰膽堿聯閤舒血寧註射液治療非酒精性脂肪性肝炎（NASH）的療效。方法將2012年1月至2013年7月收治的60例NASH患者隨機分為治療組和對照組，各30例；治療組患者靜脈滴註多烯燐脂酰膽堿和舒血寧註射液，對照組患者僅靜脈滴註多烯燐脂酰膽堿；比較兩組患者用藥前後的肝功能變化及療效。結果治療組患者肝功能指標治療後較治療前有顯著改善，且優于對照組治療後，差異均有統計學意義（P<0.05）；治療組總有效率（86.67%，26/30）高于對照組（3.33%，16/30），差異有統計學意義（χ2=7.94，P<0.01）。結論多烯燐脂酰膽堿聯閤舒血寧註射液治療NASH有顯著療效，值得臨床藉鑒。
목적：관찰다희린지선담감연합서혈저주사액치료비주정성지방성간염（NASH）적료효。방법장2012년1월지2013년7월수치적60례NASH환자수궤분위치료조화대조조，각30례；치료조환자정맥적주다희린지선담감화서혈저주사액，대조조환자부정맥적주다희린지선담감；비교량조환자용약전후적간공능변화급료효。결과치료조환자간공능지표치료후교치료전유현저개선，차우우대조조치료후，차이균유통계학의의（P<0.05）；치료조총유효솔（86.67%，26/30）고우대조조（3.33%，16/30），차이유통계학의의（χ2=7.94，P<0.01）。결론다희린지선담감연합서혈저주사액치료NASH유현저료효，치득림상차감。
Objective To observe the curative effect of polyene phosphatidylcholine injection combined with Shuxuen-ing injection in the treatment of non-alcoholic steatohepatitis(NASH). Methods A total of 60 patients with NASH,who were treated from January 2012 to June 2013 ,were randomized into treatment group and control group , 30 cases in each group. The treatment group adopted intravenous drip of polyene phosphatidylcholine and Shuxuening ,while the control group only used polyene phosphatidylcholine for intravenous drip. The changes of liver function and curative effect before and after medication between the two groups were compared. Results The liver function in the treatment group after medication improved more obvious-ly than that before medication,and the difference had statistical significance(P<0.05). The total effective rate was 86.67%(26/30) in the treatment group,which was higher than that in the control group(3.33%,16/30),and the difference had statistical significance (χ2=7.94,P<0.01). Conclusion The polyene phosphatidylcholine combined with Shuxuening injection has obvious efficacy for NASH,so it is worthy of reference in clinic.
