中外健康文摘
中外健康文摘
중외건강문적
WORLD HEALTH DIGEST
2014年
19期
10-10,11
,共2页
辛伐他汀%冠心病%调脂
辛伐他汀%冠心病%調脂
신벌타정%관심병%조지
simvastatin%coronary heart disease%lipid
目的：探讨辛伐他汀治疗冠心病患者的调脂作用的效果。方法：对2012年1月至2013年10月间来我院就诊的70例冠心病伴高血脂患者随机分为两组，观察组35例，每天给予辛伐他汀40mg治疗；对照组35例，每天给予辛伐他汀10mg治疗。结果：疗程结束后两组TC、LDL-C、TG都明显下降，HDL-C明显上升，且观察组优于对照组。两组患者不良反应差异无统计学意义(P＞0.05）。结论：两种剂量的辛伐他汀治疗均可以安全、有效地实现调脂作用，建议适当增大药物剂量，以取得更好的疗效。
目的：探討辛伐他汀治療冠心病患者的調脂作用的效果。方法：對2012年1月至2013年10月間來我院就診的70例冠心病伴高血脂患者隨機分為兩組，觀察組35例，每天給予辛伐他汀40mg治療；對照組35例，每天給予辛伐他汀10mg治療。結果：療程結束後兩組TC、LDL-C、TG都明顯下降，HDL-C明顯上升，且觀察組優于對照組。兩組患者不良反應差異無統計學意義(P＞0.05）。結論：兩種劑量的辛伐他汀治療均可以安全、有效地實現調脂作用，建議適噹增大藥物劑量，以取得更好的療效。
목적：탐토신벌타정치료관심병환자적조지작용적효과。방법：대2012년1월지2013년10월간래아원취진적70례관심병반고혈지환자수궤분위량조，관찰조35례，매천급여신벌타정40mg치료；대조조35례，매천급여신벌타정10mg치료。결과：료정결속후량조TC、LDL-C、TG도명현하강，HDL-C명현상승，차관찰조우우대조조。량조환자불량반응차이무통계학의의(P＞0.05）。결론：량충제량적신벌타정치료균가이안전、유효지실현조지작용，건의괄당증대약물제량，이취득경호적료효。
Objective: To study the lipid regulating effect of simvastatin treatment in patients with coronary artery disease effect. Methods: 70 cases of coronary heart disease from 2012 January to 2013 October in our hospital for treatment of patients with hyperlipidemia were randomly divided into two groups, 35 cases in observation group, simvastatin 40mg daily treatment; 35 cases in the control group, simvastatin 10mg treatment every day. Results: the two groups after treatment TC, LDL-C, TG were significantly decreased, HDL-C increased significantly, and the observation group was better than control group. No statistical y significant difference between the two groups of patients with adverse reactions (P > 0.05). Conclusion: simvastatin for two doses can effectively realize the lipid regulating effect, safety, to recommend appropriate dosage increase, in order to get better curative effect.
