CAJ | 학술논문

目的：探讨经皮肾镜取石(PCNL)术后尿脓毒血症的原因及防治策略。方法：回顾性分析1260例PCNL患者的临床资料。结果：1260例患者术后发生尿脓毒血症24例。其中结石直径＞2cm、鹿角形结石、术前有尿路感染、手术时间＞60分钟、术中灌注泵压力＞120mmHg 的发生率均高于对照组，组间比较差异均有统计学意义(P＜0.05)。24例患者均经抗感染、扩容等治疗后治愈。结论：结石体积大、鹿角形肾结石、术前合并尿路感染、手术时间长、灌注泵压力高是PCNL术后尿脓毒血症的危险因子。抗生素及扩容是其治疗的关键。
목적：탐토경피신경취석(PCNL)술후뇨농독혈증적원인급방치책략。방법：회고성분석1260례PCNL환자적림상자료。결과：1260례환자술후발생뇨농독혈증24례。기중결석직경＞2cm、록각형결석、술전유뇨로감염、수술시간＞60분종、술중관주빙압력＞120mmHg 적발생솔균고우대조조，조간비교차이균유통계학의의(P＜0.05)。24례환자균경항감염、확용등치료후치유。결론：결석체적대、록각형신결석、술전합병뇨로감염、수술시간장、관주빙압력고시PCNL술후뇨농독혈증적위험인자。항생소급확용시기치료적관건。
Objective:To explore the cause and strategy of prevention and treatment of urinary sepsis after percutaneous nephrolithotomy operation.Methods:The clinical data of 1260 cases of PCNL patients were retrospectively analyzed.Results:In 1260 cases,24 cases occured urinary sepsis after operation.The incidence rates of the stone diameter more than 2cm,staghorn calculi,preoperative urinary tract infection,operation time more than 60 minutes,intraoperative perfusion pump pressure more than 120mmHg were higher than those of the control group.The differences between groups were statistically significant(P<0.05).24 cases were cured by treating with anti infection and dilatancy.Conclusion:The big stone volume,antler shape kidney stones, preoperative urinary tract infection,long operation time,the high perfusion pump pressure are the risk factors for urinary sepsis after PCNL operation.Antibiotics and expansion are the key to treatment.