中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2014年
15期
65-66
,共2页
非甾体类抗炎药%上消化道出血%临床特征
非甾體類抗炎藥%上消化道齣血%臨床特徵
비치체류항염약%상소화도출혈%림상특정
Non-steroidal anti-inflammatory drugs%Upper gastrointestinal hemorrhage%Clinical features
目的：探讨非甾体类抗炎药（Non-Steroidal Anti-Inflammatory Drugs，NSAIDs）相关性上消化道出血的临床特征。方法选择因呕血或黑便就诊并行急诊胃镜检查确诊的144例患者，分为NSAIDs组和非NSAIDs组，将两组患者进行分析比较。结果NSAIDs组患者年龄≥60岁占67.7%、有消化道症状占32.3%、有心脑血管病史占61.3%、胃镜下糜烂性胃炎和胃溃疡占92.0%、HP 阳性占25.8%，与非 NSAIDs 组比较，差异有统计学意义（P<0.05）；而 NSAIDs 组患者男性占54.8%、呕血占22.6%，与非NSAIDs组比较，差异无统计学意义（P>0.05）。结论非甾体类抗炎药是上消化道出血的重要病因，伴有心脑血管疾病或病史的老年患者多见，多不伴有消化道症状和HP感染，且以胃溃疡居多。
目的：探討非甾體類抗炎藥（Non-Steroidal Anti-Inflammatory Drugs，NSAIDs）相關性上消化道齣血的臨床特徵。方法選擇因嘔血或黑便就診併行急診胃鏡檢查確診的144例患者，分為NSAIDs組和非NSAIDs組，將兩組患者進行分析比較。結果NSAIDs組患者年齡≥60歲佔67.7%、有消化道癥狀佔32.3%、有心腦血管病史佔61.3%、胃鏡下糜爛性胃炎和胃潰瘍佔92.0%、HP 暘性佔25.8%，與非 NSAIDs 組比較，差異有統計學意義（P<0.05）；而 NSAIDs 組患者男性佔54.8%、嘔血佔22.6%，與非NSAIDs組比較，差異無統計學意義（P>0.05）。結論非甾體類抗炎藥是上消化道齣血的重要病因，伴有心腦血管疾病或病史的老年患者多見，多不伴有消化道癥狀和HP感染，且以胃潰瘍居多。
목적：탐토비치체류항염약（Non-Steroidal Anti-Inflammatory Drugs，NSAIDs）상관성상소화도출혈적림상특정。방법선택인구혈혹흑편취진병행급진위경검사학진적144례환자，분위NSAIDs조화비NSAIDs조，장량조환자진행분석비교。결과NSAIDs조환자년령≥60세점67.7%、유소화도증상점32.3%、유심뇌혈관병사점61.3%、위경하미란성위염화위궤양점92.0%、HP 양성점25.8%，여비 NSAIDs 조비교，차이유통계학의의（P<0.05）；이 NSAIDs 조환자남성점54.8%、구혈점22.6%，여비NSAIDs조비교，차이무통계학의의（P>0.05）。결론비치체류항염약시상소화도출혈적중요병인，반유심뇌혈관질병혹병사적노년환자다견，다불반유소화도증상화HP감염，차이위궤양거다。
Objective To study the clinical features of upper gastrointestinal hemorrhage caused by non-steroidal anti-inflammato-ry drugs(NSAIDs).Methods 144 visited patients because of haematemesis or melena and diagnosed by emergency endoscopy were divided into NSAIDs group and non-NSAIDs group. And the patients were analyzed and compared. Results Of the NSAIDs group, patients who were 60 years or older accounted for 67.7%, had gastrointestinal symptoms accounted for 32.3%, with the history of cardiovascular or cerebrovascular diseases accounted for 61.3%, erosive gastritis and gastric ulcer detected by gastroscope account-ed for 92.0%, HP positive rate was 25.8%, compared with those of the non-NSAIDs group, the differences were statistically signifi-cant (P<0.05); in the NSAIDs group, males accounted for 54.8%, haematemesis accounted for 22.6%, compared with those of the non-NSAIDs group, the differences were not statistically significant(P>0.05). Conclusion NSAIDs are an important cause of upper gastrointestinal hemorrhage, the elderly suffering from or having the history of cardiovascular and cerebrovascular disease are easy to find. They have a higher frequency of gastric ulcer. But they have a lower frequency of gastrointestinal symptoms and HP infection .
