CAJ | 학술논문

目的：探讨药流与吸宫术对疤痕子宫再次妊娠早期终止的安全性比较。方法选取该院妇科门诊收治的要求终止早期妊娠的疤痕子宫妇女164例为研究对象，按入院顺序将患者随机分为观察组和对照组各82例。观察组采用药物米非司酮联合米索前列醇终止孕妇疤痕子宫再次早期妊娠，对照组采用吸宫术。观察两组孕妇治疗过程中出现的并发症，终止妊娠阴道出血时间、出血量异常率，流产率等，进行统计学统计，比较两组治疗的安全性。结果观察组孕妇采用药物终止早期妊娠的并发症发生率为9.76%明显低于对照组采用吸宫术孕妇28.05%，两组比较差异有统计学意义(P<0.05)；观察组孕妇阴道出血时间异常率（48.78%）、阴道出血量异常率（58.54%）及流产率为82.93%均高于吸宫术组的37.81%、47.56%及76.83%，两组比较差异无统计学意义(P>0.05)。结论采用药物对疤痕子宫再次妊娠早期终止的阴道出血量、出血时间异常率和流产率和吸宫术比较无明显差异；但是采用药物可以避免吸宫术而引起并发症的高发生率，药物流产的安全性高于吸宫术，值在临床推广。
목적：탐토약류여흡궁술대파흔자궁재차임신조기종지적안전성비교。방법선취해원부과문진수치적요구종지조기임신적파흔자궁부녀164례위연구대상，안입원순서장환자수궤분위관찰조화대조조각82례。관찰조채용약물미비사동연합미색전렬순종지잉부파흔자궁재차조기임신，대조조채용흡궁술。관찰량조잉부치료과정중출현적병발증，종지임신음도출혈시간、출혈량이상솔，유산솔등，진행통계학통계，비교량조치료적안전성。결과관찰조잉부채용약물종지조기임신적병발증발생솔위9.76%명현저우대조조채용흡궁술잉부28.05%，량조비교차이유통계학의의(P<0.05)；관찰조잉부음도출혈시간이상솔（48.78%）、음도출혈량이상솔（58.54%）급유산솔위82.93%균고우흡궁술조적37.81%、47.56%급76.83%，량조비교차이무통계학의의(P>0.05)。결론채용약물대파흔자궁재차임신조기종지적음도출혈량、출혈시간이상솔화유산솔화흡궁술비교무명현차이；단시채용약물가이피면흡궁술이인기병발증적고발생솔，약물유산적안전성고우흡궁술，치재림상추엄。
Objective To compare the safety between drug abortion and uterine aspiration for the early termination of scar uterus repregnancy. Methods 164 cases of pregnant women with scar uterus admitted in the gynecological outpatient of our hospital for early termination of pregnancy were selected as the subjects. And according to the order of admission, they were divided into the observation group and control group with 82 cases in each. The observation group was given mifepristone combined with misopros-tol for the termination of scar uterus repregnancy, and the control group was given uterine aspiration. The complications occurred during the treatment, vaginal bleeding time after termination of pregnancy, abnormal bleeding rate, abortion rate and so on of both groups were observed and counted statistically, and the safety of the treatment of two groups was compared. Results The complica-tion rate of the observation group using drugs to terminate early pregnancy was 9.76%, which was significantly lower than 28.05%of the control group using uterine aspiration, the difference was statistically significant(P<0.05);the rate of abnormal vaginal bleed-ing time, rate of abnormal vaginal bleeding amount and the abortion rate of the observation group was 48.78%,58.54%, 82.93%, respectively, which was higher than the control group's 37.81%, 47.56%, 76.83%, separately, the differences were not statistically significant(P>0.05). Conclusion There were no statistically significant differences in the rate of abnormal vaginal bleeding amount and abnormal bleeding time and abortion rate between using drugs and uterine aspiration for the termination of scar uterus repreg-nancy, but using the former way can avoid the high incidence of complications caused by uterine aspiration with higher safety, so drug abortion is worthy of clinical application.