中外健康文摘
中外健康文摘
중외건강문적
WORLD HEALTH DIGEST
2014年
16期
10-10
,共1页
甘露醇%结晶%溶解
甘露醇%結晶%溶解
감로순%결정%용해
mannitol%crystal ization%dissolving
目的:探讨甘露醇结晶溶解的最佳方法。方法:2013年1~12月选择结晶的20%甘露醇注射液共728瓶,随机分成两组,对照组362瓶使用煮沸法溶解结晶,实验组366瓶使用暖脚宝溶解结晶,观察两种结晶溶解法对甘露醇注射液瓶签破损、脱落、瓶体破裂发生情况;比较溶解后甘露醇液体的温度。结果:实验组溶解的甘露醇温度适宜,瓶体、瓶签完好,溶解后温度36.4±2.98℃,放置后无再次结晶;而对照组溶解的甘露醇瓶体破裂8瓶,标签脱落169瓶,标签破损103瓶。温度较高溶解后温度97.25±2.60℃,放置后再次结晶282瓶。两组对比差别有统计学意义( P<0.01)。结论:暖脚宝溶解、保存甘露醇结晶效果比煮熟法好。
目的:探討甘露醇結晶溶解的最佳方法。方法:2013年1~12月選擇結晶的20%甘露醇註射液共728瓶,隨機分成兩組,對照組362瓶使用煮沸法溶解結晶,實驗組366瓶使用暖腳寶溶解結晶,觀察兩種結晶溶解法對甘露醇註射液瓶籤破損、脫落、瓶體破裂髮生情況;比較溶解後甘露醇液體的溫度。結果:實驗組溶解的甘露醇溫度適宜,瓶體、瓶籤完好,溶解後溫度36.4±2.98℃,放置後無再次結晶;而對照組溶解的甘露醇瓶體破裂8瓶,標籤脫落169瓶,標籤破損103瓶。溫度較高溶解後溫度97.25±2.60℃,放置後再次結晶282瓶。兩組對比差彆有統計學意義( P<0.01)。結論:暖腳寶溶解、保存甘露醇結晶效果比煮熟法好。
목적:탐토감로순결정용해적최가방법。방법:2013년1~12월선택결정적20%감로순주사액공728병,수궤분성량조,대조조362병사용자비법용해결정,실험조366병사용난각보용해결정,관찰량충결정용해법대감로순주사액병첨파손、탈락、병체파렬발생정황;비교용해후감로순액체적온도。결과:실험조용해적감로순온도괄의,병체、병첨완호,용해후온도36.4±2.98℃,방치후무재차결정;이대조조용해적감로순병체파렬8병,표첨탈락169병,표첨파손103병。온도교고용해후온도97.25±2.60℃,방치후재차결정282병。량조대비차별유통계학의의( P<0.01)。결론:난각보용해、보존감로순결정효과비자숙법호。
Purpose:To figure out the best way of dissolving the crystal ization of mannitol.Methods:From Jan to Dec in 2013,728 bottles of 20% crystal ization of mannitol injection were randomly divided into two groups.Boiling method was used to dissolve the 362 bottles of 20% crystal ization of mannitol injection in the control group;while the electric heater method was used in the experimental group.The label damage, shedding, bottle rupture of the mannitol injection by two methods of dissolving the crystal ization were observed;the dissolving temperature was 36.4±2.98℃ with no re-crystal ization after placement.While in the control group,8 bottles were broken;169 labels were shedded,103 labels were damaged.The temperature was high at 97.25±2.60℃ after dissolving and 282 bottles were re-crystal ized after placement. There was statistical y significant difference (P<0.01) between the two groups. Conclusion:electric heater method was better than boiling method in dissolving and saving the crystal ization of mannitol.