CAJ | 학술논문

目的：分析对双相障碍躁狂发作患者临床采取阿立哌唑联合丙戊酸钠进行治疗的疗效。方法：选取我院近来3年收治的双相障碍躁狂发作患者100例，随机分为AB两组，其中A组采取阿立哌唑联合丙戊酸钠方案进行治疗，B组采取奎硫平联合丙戊酸钠方案进行治疗，对比两组患者的临床疗效。结果：A组患者的总有效率显著高于B组，其不良反应发生率明显小于B组，差异存在统计学意义（P<0.05）。另外，AB两组患者经过治疗后，其BRMS评分均有所下降，A组下降程度明显大于B组，差异存在统计学意义（P<0.05）。结论：对双相障碍躁狂发作患者临床使用阿立哌唑联合丙戊酸钠治疗，效果显著，不良反应发生率小，起效时间快，值得各大医院临床推广使用。
목적：분석대쌍상장애조광발작환자림상채취아립고서연합병무산납진행치료적료효。방법：선취아원근래3년수치적쌍상장애조광발작환자100례，수궤분위AB량조，기중A조채취아립고서연합병무산납방안진행치료，B조채취규류평연합병무산납방안진행치료，대비량조환자적림상료효。결과：A조환자적총유효솔현저고우B조，기불량반응발생솔명현소우B조，차이존재통계학의의（P<0.05）。령외，AB량조환자경과치료후，기BRMS평분균유소하강，A조하강정도명현대우B조，차이존재통계학의의（P<0.05）。결론：대쌍상장애조광발작환자림상사용아립고서연합병무산납치료，효과현저，불량반응발생솔소，기효시간쾌，치득각대의원림상추엄사용。
Objective: to analyze clinical patients with bipolar disorder manic state o take pp azole joint valproate treatment curative effect. Methods: our hospital in recent 3 years were analyzed in 100 patients with bipolar disorder manic, randomly divided into AB in the two groups, one group A state o take pp azole joint valproic acid sodium solution treatment, group B to quetiapine combined valproic acid sodium solution treatment, compared the clinical efficacy of two groups of patients. Consequence: the total effective rate in group A patients was significantly higher than that of group B, the incidence of adverse reactions are much smal er than group B, the difference is statistical y significant (P<0.05). In addition, AB two groups of patients after treatment, the BRMS scores were decreased, decline in group A was significantly greater than group B, the difference is statistical y significant (P<0.05). Conclusion: the clinical use in patients with bipolar disorder manic state o pp azole joint valproate treatment, the effect significantly, the incidence of adverse reactions, working time is fast, is worth popularizing hospitals for clinical use.