CAJ | 학술논문

目的：分析和评价局部进展期胃癌术后放疗同步化疗的疗效和不良反应。方法对我院进展期胃癌术后放疗同步化疗患者25例和单纯行化疗患者24例的临床资料进行回顾性分析，评价两组患者的1、2、3年生存率，并观察患者于治疗期间出现的不良反应。结果观察组患者的1、2、3年生存率均显著高于对照组，差异具有统计学意义；两组患者的不良反应主要表现为恶心呕吐、腹泻、骨髓抑制、肝肾损害等，其中观察组的恶心呕吐和腹泻率显著高于对照组。结论对进展期胃癌术后患者进行同步放化疗可以提高其生存率，且不良反应可耐受，值得在临床推广应用。
목적：분석화평개국부진전기위암술후방료동보화료적료효화불량반응。방법대아원진전기위암술후방료동보화료환자25례화단순행화료환자24례적림상자료진행회고성분석，평개량조환자적1、2、3년생존솔，병관찰환자우치료기간출현적불량반응。결과관찰조환자적1、2、3년생존솔균현저고우대조조，차이구유통계학의의；량조환자적불량반응주요표현위악심구토、복사、골수억제、간신손해등，기중관찰조적악심구토화복사솔현저고우대조조。결론대진전기위암술후환자진행동보방화료가이제고기생존솔，차불량반응가내수，치득재림상추엄응용。
Objective To analyze and evaluate the efficacy and adverse reactions of postoperative radiotherapy combined with radiotherapy for limited advanced gastric carcinoma. Methods The clinical data of advanced gastric cancer cases in our hospital were analyzed retrospectively. To evaluate the 1、2 and 3-year survival rate of the two groups. Besides, to observe the adverse reactions of the patients after the treatment. Results The results showed that the 1、2 and 3-year survival rate of observation group were much higher than the control groups, and the difference between these was statistical y significant. In addition, the mainly adverse reactions of the two groups were nausea, vomiting, diarrhea, bone marrow suppression, liver and kidney damage. And the rates of nausea, vomiting and diarrhea in observation group were higher than the control groups. Conclusion The concurrent chemoradiotherapy can improve the survival of advanced gastric cancer patients, and the adverse reactions were tolerated. It is worthy of the clinical application.