CAJ | 학술논문

目的：探讨苏州地区早期佝偻病及佝偻病患儿全血多元素的缺乏情况，为临床诊断及预防提供依据。方法：收集2013年1月至12月在我院确诊的佝偻病（含早期）患儿150例设为病例组，并随机选择同期在我院体检的健康婴幼儿150例设为对照组，检测比较2组儿童全血样本中的微量元素含量，以分析佝偻病患儿全血多元素缺乏情况。结果：佝偻病患儿钙(1.75±0.12)、锌(89.72±18.17)含量显著低于对照组（钙1.90±0.09，锌95.39±21.16）(P<0.05)，镁、铜、铁的含量差异无统计学意义( P>0.05)；两组儿童均存在缺铁现象，各占16.7%、19.3%。结论：钙、锌含量的检测对佝偻病的早期诊断有参考意义，但确诊仍需结合临床；苏州地区部分儿童存在铁缺乏，应及时补充。
목적：탐토소주지구조기구루병급구루병환인전혈다원소적결핍정황，위림상진단급예방제공의거。방법：수집2013년1월지12월재아원학진적구루병（함조기）환인150례설위병례조，병수궤선택동기재아원체검적건강영유인150례설위대조조，검측비교2조인동전혈양본중적미량원소함량，이분석구루병환인전혈다원소결핍정황。결과：구루병환인개(1.75±0.12)、자(89.72±18.17)함량현저저우대조조（개1.90±0.09，자95.39±21.16）(P<0.05)，미、동、철적함량차이무통계학의의( P>0.05)；량조인동균존재결철현상，각점16.7%、19.3%。결론：개、자함량적검측대구루병적조기진단유삼고의의，단학진잉수결합림상；소주지구부분인동존재철결핍，응급시보충。
Objective To provide evidence for rickets diagnosing and prevention in clinical by exploring the deficiency of microelements in rickets infants. Methods 150 cases of rickets infants and 150 healthy control col ected from January 2013 to December 2013 were designed as case and control group; the deficiency of microelements in rickets infants were analyzed by comparing the level of them in the whole blood samples of the two groups. Results The level of Ca (1.75±0.12) and Zn (89.72±18.17) in case group were significantly lower than those in control group (Ca 1.90±0.09, Zn 95.39±21.16) (P<0.05), with no statistical differences in the content of Mg, Cu and Fe. The deficiency of Fe exited in both two groups (16.7% and 19.3%, respectively). Conclusion The detection of Ca and Zn were worthy of reference for the early diagnosis of rickets, while the final diagnosis stil need to be combined with clinic; Portion of infants in Suzhou were lack of Fe, and timely supplyment should be given.