CAJ | 학술논문

目的：研究儿童精神分裂症首发患者病前行为特征与事件相关电位的关系。方法：采用Achenbach儿童行为量表，回顾性调查儿童精神分裂症首发患者在6～11岁时的行为特征。采用事件相关电位P300对患者的认知功能进行评估。用t检验比较CBCL量表高分组与低分组患者治疗前后P300各数据间的差别。结果：研究组与对照组CBCL量表社会能力总分、行为问题总分、抑郁因子分、社会退缩因子分、攻击性因子分之间差异具有统计学意义(Z=-2.820，-2.325，-2.561，-2.837，-2.759；P＜0.05)，社会能力总分与治疗前 P300潜伏期呈负相关(r=-0.231， P＜0.05)。结论：首发儿童精神分裂症患者病前社会能力与认知功能存在相关关系，社会能力较低的患者认知功能损害较严重。
목적：연구인동정신분렬증수발환자병전행위특정여사건상관전위적관계。방법：채용Achenbach인동행위량표，회고성조사인동정신분렬증수발환자재6～11세시적행위특정。채용사건상관전위P300대환자적인지공능진행평고。용t검험비교CBCL량표고분조여저분조환자치료전후P300각수거간적차별。결과：연구조여대조조CBCL량표사회능력총분、행위문제총분、억욱인자분、사회퇴축인자분、공격성인자분지간차이구유통계학의의(Z=-2.820，-2.325，-2.561，-2.837，-2.759；P＜0.05)，사회능력총분여치료전 P300잠복기정부상관(r=-0.231， P＜0.05)。결론：수발인동정신분렬증환자병전사회능력여인지공능존재상관관계，사회능력교저적환자인지공능손해교엄중。
Objective:To study the relationship between event related potentials and the premorbid behavior of the first-episode child schizophrenia.We reviewed the behavior characteristics of the first-episode child schizophrenia when they were 6 to 11 years old,who were detected by Achenbach Child Behavior Checklist.We assessed the cognitive function of patients by the event-related potential P300.We used t test to compare the difference of each P300 data before and after the treatment between the group with the CBCL scale high achievers and low achievers.Results:The difference of social competence scores,the total score of cbcl,the score of depression factor,the score of social withdrawal factor,the score of aggressive factor of the CBCL scale between the study group and the control group were statistically significant(Z=-2.820,-2.325,-2.561,-2.837,-2.759;P<0.05).The total score of social capacity and the P300 latency before the treatment was negatively correlated(r=-0.231,P<0.05).Conclusion:There are some correlation between the social abilities and cognitive function of the first-episode child schizophrenia.The lower of social ability,the more serious damage of cognitive.