CAJ | 학술논문

目的：分析原发性高血压患者24 h动态血压监测（ABPM）变化规律及临床意义。方法2011年1月至2013年9月对213例原发性高血压患者进行24 h ABPM，观察其24 h平均收缩压（24 h MSP）、24 h平均舒张压（24 h MDP）、白昼平均收缩压（dMSP）、白昼平均舒张压（dMDP）、夜间平均收缩压（nMSP）、夜间平均舒张压（nMDP）、夜间血压下降率。结果213例原发性高血压患者中100例为杓型血压，78例为非杓型血压，35例为反杓型血压。随年龄增长反杓型血压发生率明显升高，其中老年组（≥60岁）患者反杓型血压发生率较中青年组（＜60岁）高，而老年组患者杓型血压发生率较中青年组患者低，差异均有统计学意义（P＜0.05）。不同年龄段女性患者反杓型血压发生率较男性高，但二者比较，差异均无统计学意义（P＞0.05）。结论原发性高血压患者平时血压波动情况通过24 h ABPM能更加真实地反映出来。随着年龄的增长，原发性高血压患者24 h动态血压昼夜节律异常发生率不断增高，提示增龄可明确影响到原发性高血压患者的血压节律变化，应尽早进行干预治疗。
목적：분석원발성고혈압환자24 h동태혈압감측（ABPM）변화규률급림상의의。방법2011년1월지2013년9월대213례원발성고혈압환자진행24 h ABPM，관찰기24 h평균수축압（24 h MSP）、24 h평균서장압（24 h MDP）、백주평균수축압（dMSP）、백주평균서장압（dMDP）、야간평균수축압（nMSP）、야간평균서장압（nMDP）、야간혈압하강솔。결과213례원발성고혈압환자중100례위표형혈압，78례위비표형혈압，35례위반표형혈압。수년령증장반표형혈압발생솔명현승고，기중노년조（≥60세）환자반표형혈압발생솔교중청년조（＜60세）고，이노년조환자표형혈압발생솔교중청년조환자저，차이균유통계학의의（P＜0.05）。불동년령단녀성환자반표형혈압발생솔교남성고，단이자비교，차이균무통계학의의（P＞0.05）。결론원발성고혈압환자평시혈압파동정황통과24 h ABPM능경가진실지반영출래。수착년령적증장，원발성고혈압환자24 h동태혈압주야절률이상발생솔불단증고，제시증령가명학영향도원발성고혈압환자적혈압절률변화，응진조진행간예치료。
Objective To analyze the change law of 24 h ambulatory blood pressure of patients with hypertension and their clinical significance. Methods Conducted 24 h ABPM in 213 hypertensive patients from January 2011 to September 2013 , observed 24 h mean systolic blood pressure(24 h MSBP),24 h mean diastolic blood pressure(24 h MDBP),daytime systolic blood pressure(dMSBP),daytime diastolic blood pressure(dMDBP),nighttime systolic blood pressure(nMSBP),average nighttime di astolic blood pressure(nMDBP),nighttime blood pressure rates. Results Among the 213 patients,100 were diagnosed as dipper type blood pressure,78 as non-dipper blood pressure and 35 as anti-dipper type blood pressure. The incidence rate of the anti-dip-per type was increased with age growing,in which,the incidence rate of the anti-dipper type of the aged(60 years) was higher than that of the young and middle-aged(<60 years old),while the incidence rate of the dipper type was lower than that of the young and middle-aged. Both of the differences were statistically significant (P<0.05). The incidence rate of the anti-dipper type of the female in different age was higher than that of the male. The differences of the two had no statistical significance (P<0.05). Conclusion Blood pressure fluctuations in the patients in peacetime are able to be reflected truly by 24 h ABPM. With increasing age ,the oc-currence rate of 24 h ambulatory blood pressure abnormal circadian rhythms of the primary hypertensive patients was accordingly increased constantly. It is indicated that the aging can give a definite impact on the change of hypertension rhythms of the primary hypertensive patients,It should adopt intervention measures as early as possible.