中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
19期
85-86
,共2页
肺心病%心力衰竭%参麦注射液%脑利钠肽%末端脑钠肽前体
肺心病%心力衰竭%參麥註射液%腦利鈉肽%末耑腦鈉肽前體
폐심병%심력쇠갈%삼맥주사액%뇌리납태%말단뇌납태전체
Pulmonary heart disease%Heart failure%Shenmai injection%Brain natriuretic peptide%Pro-brain natriuretic peptide
目的：探讨参麦注射液对慢性肺心病心力衰竭患者血浆BNP、NT-proBNP的影响。方法：将86例慢性肺心病心力衰竭患者随机分为治疗组和对照组各43例，对照组采用常规治疗，治疗组在常规治疗基础上加用参麦注射液，疗程2周。测定治疗前后血浆BNP、NT-proBNP浓度。结果：治疗后两组血浆BNP、NT-proBNP水平较治疗前均有明显下降，而治疗组与对照组比较，治疗后血浆BNP、NT-proBNP水平较治疗前均下降更显著，差异有统计学意义(P＜0.01)；治疗2周后，两组患者的EF、△D%、△T%、Emax、Emax/Amax均有增加，与对照组相比，治疗组增加更为显著，差异有统计学意义(P＜0.01)；而两组治疗后比较差异有统计学意义(P＜0.01)。结论：参麦注射液能提高左室收缩功能，并可降低血浆BNP及NT-proBNP水平，且不良反应小，是治疗慢性肺心病心力衰竭的有效辅助药物，值得在临床推广。
目的：探討參麥註射液對慢性肺心病心力衰竭患者血漿BNP、NT-proBNP的影響。方法：將86例慢性肺心病心力衰竭患者隨機分為治療組和對照組各43例，對照組採用常規治療，治療組在常規治療基礎上加用參麥註射液，療程2週。測定治療前後血漿BNP、NT-proBNP濃度。結果：治療後兩組血漿BNP、NT-proBNP水平較治療前均有明顯下降，而治療組與對照組比較，治療後血漿BNP、NT-proBNP水平較治療前均下降更顯著，差異有統計學意義(P＜0.01)；治療2週後，兩組患者的EF、△D%、△T%、Emax、Emax/Amax均有增加，與對照組相比，治療組增加更為顯著，差異有統計學意義(P＜0.01)；而兩組治療後比較差異有統計學意義(P＜0.01)。結論：參麥註射液能提高左室收縮功能，併可降低血漿BNP及NT-proBNP水平，且不良反應小，是治療慢性肺心病心力衰竭的有效輔助藥物，值得在臨床推廣。
목적：탐토삼맥주사액대만성폐심병심력쇠갈환자혈장BNP、NT-proBNP적영향。방법：장86례만성폐심병심력쇠갈환자수궤분위치료조화대조조각43례，대조조채용상규치료，치료조재상규치료기출상가용삼맥주사액，료정2주。측정치료전후혈장BNP、NT-proBNP농도。결과：치료후량조혈장BNP、NT-proBNP수평교치료전균유명현하강，이치료조여대조조비교，치료후혈장BNP、NT-proBNP수평교치료전균하강경현저，차이유통계학의의(P＜0.01)；치료2주후，량조환자적EF、△D%、△T%、Emax、Emax/Amax균유증가，여대조조상비，치료조증가경위현저，차이유통계학의의(P＜0.01)；이량조치료후비교차이유통계학의의(P＜0.01)。결론：삼맥주사액능제고좌실수축공능，병가강저혈장BNP급NT-proBNP수평，차불량반응소，시치료만성폐심병심력쇠갈적유효보조약물，치득재림상추엄。
Objective:To explore the effect of Shenmai injection on the plasma BNP,NT-proBNP of patients with chronic pulmonary heart disease heart failure.Methods:86 cases with chronic pulmonary heart disease heart failure were randomly divided into the treatment group and the control group with 43 cases in each.The control group were treated with conventional treatment. The treatment group were treated with Shenmai injection on the basis of conventional treatment.The course of treatment was 2 weeks.The plasma BNP,NT-proBNP concentration were measured before and after the treatment.Results:After the treatment,the plasma BNP,NT-proBNP levels of the two groups were significantly decreased than those before treatment. Compared with the control group, the plasma BNP,NT-proBNP levels of the treatment group after treatment were more significantly decreased than those before treatment(P<0.01).After 2 weeks of the treatment,EF,△D%,△T%,Emax,Emax/Amax of the two groups were increased.Compared with the control group,the treatment group were more significantly increased(P<0.01).The two groups after treatment were significantly different(P<0.01).Conclusion:Shenmai injection can improve the left ventricular systolic function,and reduce the plasma BNP and NT-proBNP levels.It has less adverse reactions.It is an effective adjunctive medicine in the treatment of chronic pulmonary heart disease heart failure.It is worth in clinical promotion.
