中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
19期
65-66
,共2页
米非司酮%甲氨蝶呤%异位妊娠
米非司酮%甲氨蝶呤%異位妊娠
미비사동%갑안접령%이위임신
Mifepristone%Methotrexate%Ectopic pregnancy
目的：研究米非司酮联合甲氨蝶呤治疗异位妊娠的临床疗效。方法：2012年7月-2013年7月收治异位妊娠患者58例，随机将患者分为对照组和观察组，每组29例。对照组采取米非司酮作为治疗性药物给予处理；观察组在对照组的治疗基础上，增加甲氨蝶呤进行联合治疗。治疗周期结束之后，比较两组的治疗效果，并采取统计学分析。结果：经过治疗之后，观察组总治疗有效率89.5%。对照组总治疗有效率57.9%。两组比较差异有统计学意义(P＜0.05)。观察组在住院时间、β-HCG恢复时间、阴道无规则出血时间、腹痛时间均优于对照组，差异均有统计学意义(P＜0.05)。两组在药物不良反应的比较上差异无统计学意义(P＞0.05)。结论：米非司酮联合甲氨蝶呤治疗异位妊娠具有良好效果，值得在临床上大力推广。
目的：研究米非司酮聯閤甲氨蝶呤治療異位妊娠的臨床療效。方法：2012年7月-2013年7月收治異位妊娠患者58例，隨機將患者分為對照組和觀察組，每組29例。對照組採取米非司酮作為治療性藥物給予處理；觀察組在對照組的治療基礎上，增加甲氨蝶呤進行聯閤治療。治療週期結束之後，比較兩組的治療效果，併採取統計學分析。結果：經過治療之後，觀察組總治療有效率89.5%。對照組總治療有效率57.9%。兩組比較差異有統計學意義(P＜0.05)。觀察組在住院時間、β-HCG恢複時間、陰道無規則齣血時間、腹痛時間均優于對照組，差異均有統計學意義(P＜0.05)。兩組在藥物不良反應的比較上差異無統計學意義(P＞0.05)。結論：米非司酮聯閤甲氨蝶呤治療異位妊娠具有良好效果，值得在臨床上大力推廣。
목적：연구미비사동연합갑안접령치료이위임신적림상료효。방법：2012년7월-2013년7월수치이위임신환자58례，수궤장환자분위대조조화관찰조，매조29례。대조조채취미비사동작위치료성약물급여처리；관찰조재대조조적치료기출상，증가갑안접령진행연합치료。치료주기결속지후，비교량조적치료효과，병채취통계학분석。결과：경과치료지후，관찰조총치료유효솔89.5%。대조조총치료유효솔57.9%。량조비교차이유통계학의의(P＜0.05)。관찰조재주원시간、β-HCG회복시간、음도무규칙출혈시간、복통시간균우우대조조，차이균유통계학의의(P＜0.05)。량조재약물불량반응적비교상차이무통계학의의(P＞0.05)。결론：미비사동연합갑안접령치료이위임신구유량호효과，치득재림상상대력추엄。
Objective:To study the clinical effect of mifepristone combined with methotrexate in the treatment of ectopic pregnancy.Methods:58 cases with ectopic pregnancy were selected from July 2012 to July 2013.They were randomly divided into the control group and the observation group with 29 cases in each.The control group took mifepristone as the treatment drugs for treatment.On the basis of the treatment in the control group,the observation group increased methotrexate combined treatment. After the end of treatment period,the treatment effects of the two groups were compared.It took statistical analysis.Results:After treatment,the total treatment effective rate of the observation group was 89.5%.The total treatment effective rate of the control group was 57.9%.Comparing the two groups,there had significant difference(P<0.05).The hospital stay,β-HCG recovery time, vaginal irregular bleeding time and abdominal pain time of the observation group were better than that of the control group.There all had significant difference(P<0.05).There was no significant difference between two groups in adverse drug reactions of comparison(P>0.05).Conclusion:In clinical on the patients with ectopic pregnancy,taking mifepristone combined with methotrexate treatment has a good effect.It is worth popularizing in clinic.
