CAJ | 학술논문

探讨静脉注射胺碘酮不良反应观察及护理要点。方法对本院2008年1月～2012年1月应用静脉注射胺碘酮的150例患者发生不良反应情况进行统计分析。结果150例患者使用胺碘酮治疗7 d 后，141例心律失常恢复，总有效率94.0%，其中有46例（30.7%）出现不良反应，包括肺毒性20例，甲状腺功能障碍13例，窦性心动过缓或房室传导阻滞6例，消化系统紊乱3例，低血压2例，光敏感和震颤各1例。结论静脉注射胺碘酮易引起肺部、心血管系统、消化系统等不良反应，用药期间密切观察患者反应，一旦出现立即对症处理。
탐토정맥주사알전동불량반응관찰급호리요점。방법대본원2008년1월～2012년1월응용정맥주사알전동적150례환자발생불량반응정황진행통계분석。결과150례환자사용알전동치료7 d 후，141례심률실상회복，총유효솔94.0%，기중유46례（30.7%）출현불량반응，포괄폐독성20례，갑상선공능장애13례，두성심동과완혹방실전도조체6례，소화계통문란3례，저혈압2례，광민감화진전각1례。결론정맥주사알전동역인기폐부、심혈관계통、소화계통등불량반응，용약기간밀절관찰환자반응，일단출현립즉대증처리。
Objective To explore the adverse reactions of intravenous infusion of amiodarone and summerize nursing key points.Method The histories of 150 patients with intravenous amiodarone from January 2008 to January 2012 were retrospectively reviewed for investigation of adverse reactions.Results After 150 patients received 7-day treatment with intravenous infusion of amiodarone, arrhythmia in 141 of them disappeared, with the total effective rate of 94.0 %. Fourty-six of them(30.7 %)came out with adverse reactions including lung toxicity(20 cases), thyroid dysfunction(13 cases), sinus bradycardia or atrioventricular block(6 cases), digestive disorder(3 cases), hypotension(2 cases), photaesthesia(1 case)and tremor(1 case).Conclusions The patients with intravenous infusion of amiodarone are susceptible to certain adverse reactions in lung, cardiovascular system, nervous system and digestive system. Close observation is necessary so as to render pertinent treatments.