中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
22期
35-35,37
,共2页
联合用药%胃溃疡%Hp感染%临床分析
聯閤用藥%胃潰瘍%Hp感染%臨床分析
연합용약%위궤양%Hp감염%림상분석
Combined use of drugs%Gastric ulcer%Helicobacter pylori infection%The clinical analysis
目的：探讨联合用药治疗胃溃疡幽门螺杆菌(Hp)感染临床疗效。方法：2013年3月-2014年3月收治胃溃疡Hp感染患者80例，随机分为对照组和观察组各40例。对照组给予阿莫西林、克拉霉素、胶体果胶铋和奥美拉唑联合治疗，观察组给予阿莫西林、埃索美拉唑、胶体果胶铋和左氧氟沙星。观察对比两组治疗后的临床疗效、Hp阳性率和胃溃疡的复发率。结果：观察组总有效率95%(38/40)，显效25例，有效13例；对照组总有效率70%，显效10例，有效18例，两组有效率差异具有统计学意义(P＜0.05)。观察组和对照组的Hp阳性率分别为2.5%、15%，胃溃疡的复发率分别为10%、22.5%，差异有统计学意义(P＜0.05)。结论：联合应用阿莫西林、埃索美拉唑、胶体果胶铋及左氧氟沙星能有效清除Hp，提高治疗效果，降低胃溃疡的复发率。
目的：探討聯閤用藥治療胃潰瘍幽門螺桿菌(Hp)感染臨床療效。方法：2013年3月-2014年3月收治胃潰瘍Hp感染患者80例，隨機分為對照組和觀察組各40例。對照組給予阿莫西林、剋拉黴素、膠體果膠鉍和奧美拉唑聯閤治療，觀察組給予阿莫西林、埃索美拉唑、膠體果膠鉍和左氧氟沙星。觀察對比兩組治療後的臨床療效、Hp暘性率和胃潰瘍的複髮率。結果：觀察組總有效率95%(38/40)，顯效25例，有效13例；對照組總有效率70%，顯效10例，有效18例，兩組有效率差異具有統計學意義(P＜0.05)。觀察組和對照組的Hp暘性率分彆為2.5%、15%，胃潰瘍的複髮率分彆為10%、22.5%，差異有統計學意義(P＜0.05)。結論：聯閤應用阿莫西林、埃索美拉唑、膠體果膠鉍及左氧氟沙星能有效清除Hp，提高治療效果，降低胃潰瘍的複髮率。
목적：탐토연합용약치료위궤양유문라간균(Hp)감염림상료효。방법：2013년3월-2014년3월수치위궤양Hp감염환자80례，수궤분위대조조화관찰조각40례。대조조급여아막서림、극랍매소、효체과효필화오미랍서연합치료，관찰조급여아막서림、애색미랍서、효체과효필화좌양불사성。관찰대비량조치료후적림상료효、Hp양성솔화위궤양적복발솔。결과：관찰조총유효솔95%(38/40)，현효25례，유효13례；대조조총유효솔70%，현효10례，유효18례，량조유효솔차이구유통계학의의(P＜0.05)。관찰조화대조조적Hp양성솔분별위2.5%、15%，위궤양적복발솔분별위10%、22.5%，차이유통계학의의(P＜0.05)。결론：연합응용아막서림、애색미랍서、효체과효필급좌양불사성능유효청제Hp，제고치료효과，강저위궤양적복발솔。
Objective:To explore the clinical effect of combination therapy in the treatment of gastric ulcer infected with Helicobacter pylori.Methods:80 cases with gastric ulcer infected with Helicobacter pylori were selected from 2013 March to 2014 March.They were randomly divided into the control group and the observation group with 40 cases in each.The control group were treated with amoxicillin,clarithromycin,colloidal bismuth pectin and omeprazole,amoxicillin.The observation group were treated with esomeprazole,colloidal bismuth pectin and levofloxacin.We observed and compared the clinical curative effect after the treatment,the positive rate of Helicobacter pylorus and gastric ulcer recurrence rate of the two groups.Results:In the observation group,the total efficiency was 95%(38/40);25 cases were markedly effective;13 cases were effective.In the control group,the total efficiency was 70%;10 cases were markedly effective;18 cases were effective.The difference was statistically significant(P<0.05). In the observation group and the control group,the positive rate of Helicobacter pylori were respectively 2.5% and 15%;gastric ulcer recurrence rates were respectively 10% and 22.5% .The difference was statistically significant(P<0.05).Conclusion:The combination application of amoxicillin, esomeprazole,colloidal bismuth pectin and levofloxacin can effectively clear Helicobacter pylori,improve the therapeutic effect,and reduce the recurrence rate of gastric ulcer.
