CAJ | 학술논문

清醒气管插管是临床工作中处理困难气道的常用方式，恰当使用镇痛镇静药物是保证插管成功的重要辅助手段。右美托咪定是一种高效和高选择性的α2肾上腺素能受体激动剂，具有镇静镇痛、抑制交感神经活性、抑制炎症反应、心肌保护、抑制应激相关的恐惧记忆和学习等作用。现就上述作用在清醒气管插管中的应用及相关的研究进展进行综述。
청성기관삽관시림상공작중처리곤난기도적상용방식，흡당사용진통진정약물시보증삽관성공적중요보조수단。우미탁미정시일충고효화고선택성적α2신상선소능수체격동제，구유진정진통、억제교감신경활성、억제염증반응、심기보호、억제응격상관적공구기억화학습등작용。현취상술작용재청성기관삽관중적응용급상관적연구진전진행종술。
Awake tracheal intubation is a common way to difficult airway in clinical work, the appropriate use of analgesic and sedative drugs is an important supplementary means of successful intubation. Dexmedetomidine is a kind of high efficient and high selective α2 adrenergic receptor agonist, with sedation and analgesia, restraining the activity of sympathetic nerve, inhibiting the inflammatory reaction, myocardial protection, restraint stress related fear memory and learning effect, this article reviews the progress in the application in the awake tracheal intubation and related research.