CAJ | 학술논문

目的：探讨改良封闭负压引流联合重组人表皮生长因子治疗腹部术口愈合不良的效果。方法选择2011年1～12月在本院治疗腹部术口愈合不良患者50例为对照组，在抗感染治疗基础上，采用传统清创+利凡诺液或硫酸庆大霉素换药，配合红外线治疗；选择2012年1月～2013年6月在本院治疗腹部术口愈合不良患者63例为实验组，在抗感染治疗基础上，采用清创+人重组表面生长因子+改良封闭负压引流治疗。比较两组患者换药次数、每次换药时间、换药费用及术口愈合时间情况。结果两组患者换药费用比较，P＞0.05，差异无统计学意义；换药次数、每次换药时间、术口愈合时间比较，均P＜0.001，差异具有统计学意义，实验组换药次数、术口愈合时间明显短于对照组，每次换药时间明显长于对照组。结论改良封闭负压引流联合重组人表皮生长因子，治疗腹部术口愈合不良能加速创面愈合，减少换药次数，缩短住院时间，从而减轻患者经济负担，适宜在基层医院推广应用。
목적：탐토개량봉폐부압인류연합중조인표피생장인자치료복부술구유합불량적효과。방법선택2011년1～12월재본원치료복부술구유합불량환자50례위대조조，재항감염치료기출상，채용전통청창+리범낙액혹류산경대매소환약，배합홍외선치료；선택2012년1월～2013년6월재본원치료복부술구유합불량환자63례위실험조，재항감염치료기출상，채용청창+인중조표면생장인자+개량봉폐부압인류치료。비교량조환자환약차수、매차환약시간、환약비용급술구유합시간정황。결과량조환자환약비용비교，P＞0.05，차이무통계학의의；환약차수、매차환약시간、술구유합시간비교，균P＜0.001，차이구유통계학의의，실험조환약차수、술구유합시간명현단우대조조，매차환약시간명현장우대조조。결론개량봉폐부압인류연합중조인표피생장인자，치료복부술구유합불량능가속창면유합，감소환약차수，축단주원시간，종이감경환자경제부담，괄의재기층의원추엄응용。
Objective To explore the curative effect of modified closed negative pressure drainage on abnormal abdominal incision. Methods Sity-three patients with abnormal healing of abdominal incision in our hospital from January 2012 to June 2013 were selected as the observation group. Another 50 patients from January to December 2011 were assigned to the control group. The former was treated after debridement with human recombinant surface growth factor and modified closed negative pressure drainage,while the latter after debridement with anti-infection and dressings of ethacridine or gentamicinsolution as well as with infrared therapy. The two groups were compared in terms of the frequency,time and cost of changed dressings,and the healing time of the incisions.Results There was insignificant difference in the cost of changed dressings between the two groups(P>0.05). However,the differences were statistically significant in terms of the frequency and time of changed dressings and the healing time of the incisions(P<0.05). The observation group was significantly superior to the control group.Conclusions Modified closed negative pressure drainage is effective in accelerating the healing in abnormal abdominal incisions,reducing the frequency and the time of changed dressings,and easing the economic burdens of the patients,which is suggested to be popularized and applicable in the pimary hospitals.