中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
26期
105-106
,共2页
血清降钙素原%细菌感染%血清水平%阳性率
血清降鈣素原%細菌感染%血清水平%暘性率
혈청강개소원%세균감염%혈청수평%양성솔
Serum procalcitonin%Bacterial infection%The serum level%The positive rate
目的：探析血清降钙素原的变化在细菌感染性疾病中所发挥的评估作用。方法：2013年10月-2014年3月收治感染患者100例，根据患者出院诊断结果将细菌感染性疾病患者作为观察组，对照组为非细菌性感染患者。两组均于清晨空腹采集3 mL不抗凝静脉血，PCT测定使用电化学发光免疫分析法，CRP测定使用免疫比浊法，比较两种检测结果的变化。结果：观察组中不同感染类型患者的RCT与CRP的测量结果均存在一定差异，但与对照组相比明显升高，RCT与CRP结果主要随感染程度的加重而升高，两组对比差异有统计学意义(P＜0.05)。在阳性率的比较上，观察组PCT测定的阳性检出率90.32%，CRP的阳性检出率80.64%；对照组PCT阳性检出率21.05%，CRP阳性检出率68.42%。PCT 检测结果的对比差异具有统计学意义(P＜0.05)，CRP 结果的对比差异无统计学意义(P＞0.05)。结论：PCT在细菌感染性疾病中的检测具有较高的敏感性，对患者血清中PCT含量进行动态检测可以有效鉴别患者的感染是否属于细菌性感染，同时根据PCT水平判断患者的感染程度，为治疗以及预后提供有利依据。
目的：探析血清降鈣素原的變化在細菌感染性疾病中所髮揮的評估作用。方法：2013年10月-2014年3月收治感染患者100例，根據患者齣院診斷結果將細菌感染性疾病患者作為觀察組，對照組為非細菌性感染患者。兩組均于清晨空腹採集3 mL不抗凝靜脈血，PCT測定使用電化學髮光免疫分析法，CRP測定使用免疫比濁法，比較兩種檢測結果的變化。結果：觀察組中不同感染類型患者的RCT與CRP的測量結果均存在一定差異，但與對照組相比明顯升高，RCT與CRP結果主要隨感染程度的加重而升高，兩組對比差異有統計學意義(P＜0.05)。在暘性率的比較上，觀察組PCT測定的暘性檢齣率90.32%，CRP的暘性檢齣率80.64%；對照組PCT暘性檢齣率21.05%，CRP暘性檢齣率68.42%。PCT 檢測結果的對比差異具有統計學意義(P＜0.05)，CRP 結果的對比差異無統計學意義(P＞0.05)。結論：PCT在細菌感染性疾病中的檢測具有較高的敏感性，對患者血清中PCT含量進行動態檢測可以有效鑒彆患者的感染是否屬于細菌性感染，同時根據PCT水平判斷患者的感染程度，為治療以及預後提供有利依據。
목적：탐석혈청강개소원적변화재세균감염성질병중소발휘적평고작용。방법：2013년10월-2014년3월수치감염환자100례，근거환자출원진단결과장세균감염성질병환자작위관찰조，대조조위비세균성감염환자。량조균우청신공복채집3 mL불항응정맥혈，PCT측정사용전화학발광면역분석법，CRP측정사용면역비탁법，비교량충검측결과적변화。결과：관찰조중불동감염류형환자적RCT여CRP적측량결과균존재일정차이，단여대조조상비명현승고，RCT여CRP결과주요수감염정도적가중이승고，량조대비차이유통계학의의(P＜0.05)。재양성솔적비교상，관찰조PCT측정적양성검출솔90.32%，CRP적양성검출솔80.64%；대조조PCT양성검출솔21.05%，CRP양성검출솔68.42%。PCT 검측결과적대비차이구유통계학의의(P＜0.05)，CRP 결과적대비차이무통계학의의(P＞0.05)。결론：PCT재세균감염성질병중적검측구유교고적민감성，대환자혈청중PCT함량진행동태검측가이유효감별환자적감염시부속우세균성감염，동시근거PCT수평판단환자적감염정도，위치료이급예후제공유리의거。
Objective:To explore the evaluation function of changes of serum procalcitonin in bacterial infection.Methods:100 cases with infection were selected from October 2013 to March 2014.According to the patient's discharge diagnosis results, bacterial infectious disease patients were as the observation group,and non bacterial infection patients were as the control group.3 mL not anticoagulated venous blood were selected in the early morning of the two groups.PCT was measured using electrochemical luminescence assay,and CRP was measured using immunoturbidimetric method.We compared the changes of two detection results.Results:In the observation group,the results of RCT and CRP in patients with different types of infection were different,but compared with the control group,it was significantly increased.RCT and CRP results were increased with the increased degree of infection.Two groups had significant difference,and the difference was statistically significant(P<0.05).In comparing the positive rate,in the observation group,the positive rate of PCT was 90.32%,and the positive rate of CRP was 80.64%. In the control group,the PCT positive rate was 21.05% ,and CRP positive rate was 68.42% .There was statistical significance compared with results of PCT test(P<0.05),and there was no significant difference compared with the CRP results(P>0.05). Conclusion:The PCT detection has higher sensitivity in bacterial infections.Dynamic PCT content of serum detection can effectively identify patients infection for bacterial infection.According to the PCT level,we can judge the degree of infection for patients.It can provide the advantageous basis for treatment and prognosis.
