CAJ | 학술논문

目的：探讨血清黄体酮对早期宫内妊娠及异常妊娠的预测意义。方法选择该院住院部2012年10月至2013年5月收治的早孕妇女214例（停经时间为4～8周），采用化学发光法检测血清黄体酮、血清绒毛膜促性腺激素（HCG），动态监测并联合B超对早期正常妊娠及异常妊娠进行筛查、随访。结果214例患者中早期宫内妊娠110例，自然流产47例，异位妊娠57例。三组研究对象的年龄、β-HCG、黄体酮水平比较，差异均有统计学意义（P<0.05）；logistic回归分析显示黄体酮与早孕期妊娠结局相关；当黄体酮大于63.6 nmol/L时自然流产和异位妊娠的发生率明显降低；理想的维持妊娠的黄体酮水平应为63.6~95.4 nmol/L。结论监测早孕期血清HCG和黄体酮水平对妊娠结局有预测价值。
목적：탐토혈청황체동대조기궁내임신급이상임신적예측의의。방법선택해원주원부2012년10월지2013년5월수치적조잉부녀214례（정경시간위4～8주），채용화학발광법검측혈청황체동、혈청융모막촉성선격소（HCG），동태감측병연합B초대조기정상임신급이상임신진행사사、수방。결과214례환자중조기궁내임신110례，자연유산47례，이위임신57례。삼조연구대상적년령、β-HCG、황체동수평비교，차이균유통계학의의（P<0.05）；logistic회귀분석현시황체동여조잉기임신결국상관；당황체동대우63.6 nmol/L시자연유산화이위임신적발생솔명현강저；이상적유지임신적황체동수평응위63.6~95.4 nmol/L。결론감측조잉기혈청HCG화황체동수평대임신결국유예측개치。
Objective To investigate the predictive value of serum progesterone (P) to early uterine pregnancy and ab-normal pregnancy. Methods A total of 214 women with early pregnancy(menopause time was 4-8 weeks),who were received in the hospital from October 2012 to May 2013,were selected and detected on P,human chorionic gonadotropin(HCG) by chemilu-minescence method,and dynamic monitoring combined with B ultrasound was adopted for screening and follow-up. Results A-mong the 214 cases,there were 110 cases with early intrauterine pregnancy,47 cases with spontaneous abortion and 57 cases with ectopic pregnancy. The comparison of age,β-HCG and P among the three kinds of pregnancy showed statistically significant dif ference(P<0.05);Logistic regression analysis showed that P level was associated with the outcomes of the early pregnancy,when P>63.6 nmol/L,the incidence of the spontaneous abortion and ectopic pregnancy was significantly reduced,and the ideal level for maintaining the pregnancy of P was 63.6-95.4 nmol/mL. Conclusion It is an effective way to predict the pregnancy outcomes by monitoring the serum HCG and P level in early pregnancy.