现代医药卫生
現代醫藥衛生
현대의약위생
MODERN MEDICINE HEALTH
2014年
20期
3061-3063
,共3页
乳腺肿瘤%预后%未触及肿块早期乳腺癌%临床特征%生存率
乳腺腫瘤%預後%未觸及腫塊早期乳腺癌%臨床特徵%生存率
유선종류%예후%미촉급종괴조기유선암%림상특정%생존솔
Breast neoplasms%Prognosis%Non-palpable early breast cancer%Clinic-pathological features%Prog-nostic analysis
目的：探讨未触及肿块早期乳腺癌患者的临床特征、生存率和影响预后的因素。方法回顾性分析2000年1月至2012年12月收治的121例未触及肿块的早期乳腺癌患者的临床资料，观察患者长期生存率，分析其临床特征及影响预后的因素。结果121例未触及肿块的早期乳腺癌患者发病年龄21~69岁，平均（44.1±10.6）岁，＜50岁者占71.1%（86/121）；64.5%（78/121）患者主要因乳头溢乳、乳腺腺体增厚等临床某一细微的早期变化进行追踪检查而发现；主要病理类型为浸润性非特殊癌[64.5%（78/121）]，雌、孕激素受体均阳性者占60.3%（73/121）。5年总体生存率为84.9%，年龄、家族史、雌激素受体状况及组织病理学类型是影响患者预后的独立指标。结论未触及肿块早期乳腺癌患者具有独特的临床和病理特征，影响患者生存、预后的独立因素为年龄、家族史、雌激素受体状况及组织病理学类型。
目的：探討未觸及腫塊早期乳腺癌患者的臨床特徵、生存率和影響預後的因素。方法迴顧性分析2000年1月至2012年12月收治的121例未觸及腫塊的早期乳腺癌患者的臨床資料，觀察患者長期生存率，分析其臨床特徵及影響預後的因素。結果121例未觸及腫塊的早期乳腺癌患者髮病年齡21~69歲，平均（44.1±10.6）歲，＜50歲者佔71.1%（86/121）；64.5%（78/121）患者主要因乳頭溢乳、乳腺腺體增厚等臨床某一細微的早期變化進行追蹤檢查而髮現；主要病理類型為浸潤性非特殊癌[64.5%（78/121）]，雌、孕激素受體均暘性者佔60.3%（73/121）。5年總體生存率為84.9%，年齡、傢族史、雌激素受體狀況及組織病理學類型是影響患者預後的獨立指標。結論未觸及腫塊早期乳腺癌患者具有獨特的臨床和病理特徵，影響患者生存、預後的獨立因素為年齡、傢族史、雌激素受體狀況及組織病理學類型。
목적：탐토미촉급종괴조기유선암환자적림상특정、생존솔화영향예후적인소。방법회고성분석2000년1월지2012년12월수치적121례미촉급종괴적조기유선암환자적림상자료，관찰환자장기생존솔，분석기림상특정급영향예후적인소。결과121례미촉급종괴적조기유선암환자발병년령21~69세，평균（44.1±10.6）세，＜50세자점71.1%（86/121）；64.5%（78/121）환자주요인유두일유、유선선체증후등림상모일세미적조기변화진행추종검사이발현；주요병리류형위침윤성비특수암[64.5%（78/121）]，자、잉격소수체균양성자점60.3%（73/121）。5년총체생존솔위84.9%，년령、가족사、자격소수체상황급조직병이학류형시영향환자예후적독립지표。결론미촉급종괴조기유선암환자구유독특적림상화병리특정，영향환자생존、예후적독립인소위년령、가족사、자격소수체상황급조직병이학류형。
Objective To analyze the clinical features,survival rate and prognostic factors of early breast cancer with nonpalpable mass. Methods Clinical data of 121 non-palpable early breast cancer patients treated from January 2000 to De-cember 2012 were retrospectively reviewed to analyze clinical features,survival rate and prognostic factors. Results The onset age of the 121 cases were 21-69 years old,with the average age of (44.1±10.6) years,and the patients less than 50 years account-ed for 71.1%(86/121);64.5%(78/121) patients were found by follow-up examination of nipple discharge,thickening of mammary gland and so on;the main pathological type was infiltrative non specific cancer[64.5%(78/121)],and in estrogen and progesterone receptors,the positive accounted for 60.3%(73/121). The 5-year survival rate was 84.9%. The age,family history,estrogen recep-tor status and tumor pathohistology were the independent prognostic factors. Conclusions Non-palpable early breast cancer ex-hibits distinctive clinical and pathological features. Age,family history,estrogen receptor status and tumor pathohistrology are in-dependent prognostic factors.
