CAJ | 학술논문

目的：探讨舒肝解郁胶囊合并莫沙必利对老年功能性便秘的临床治疗效果。方法：本研究设计使用随机双盲对照研究的方法。入组老年功能性便秘患者共68例，将患者随机分为研究组34例和对照组34例。研究组使用莫沙必利辅以舒肝解郁胶囊治疗，对照组使用莫沙必利治疗。两组分别治疗4周。观察两组治疗前后的排便次数和大便性状，并对排便困难症状进行评分。结果：与对照组比较，研究组治疗后的排便次数明显增加，大便性状改善显著(P＜0.05)。两组排便困难症状评分均下降(P＜0.05)，但研究组与对照组组间比较差异无统计学意义(P＞0.05)。结论：舒肝解郁胶囊能辅助莫沙必利减轻老年功能性便秘患者的症状。
목적：탐토서간해욱효낭합병막사필리대노년공능성편비적림상치료효과。방법：본연구설계사용수궤쌍맹대조연구적방법。입조노년공능성편비환자공68례，장환자수궤분위연구조34례화대조조34례。연구조사용막사필리보이서간해욱효낭치료，대조조사용막사필리치료。량조분별치료4주。관찰량조치료전후적배편차수화대편성상，병대배편곤난증상진행평분。결과：여대조조비교，연구조치료후적배편차수명현증가，대편성상개선현저(P＜0.05)。량조배편곤난증상평분균하강(P＜0.05)，단연구조여대조조조간비교차이무통계학의의(P＞0.05)。결론：서간해욱효낭능보조막사필리감경노년공능성편비환자적증상。
Objective:To investigate the clinical therapeutic effect of Shu Gan Jie Yu capsule combined with mosapride in the treatment of senile functional constipation.Methods:In this study we used a randomized double-blind controlled clinical trial.68 patients with senile functional constipation were randomly divided into the study group and the control group with 34 cases in each.Study group used Mosapride combined with Shu Gan Jie Yu capsule treatment,and the control group only used mosapride. Both of the two groups were treated for 4 weeks.Then we observed the stool frequency and stool in the two groups before and after the treatment,and scored the defecate difficulty symptom.Results:When compared with the control group,the defecation frequency of the study group was significantly increased,and the stool was also significantly improved(P<0.05).Defecate difficulty symptom score of two groups were decreased(P<0.05),but there was no statistically difference between the study group and the control groups(P>0.05).Conclusion:Shu Gan Jie Yu capsule combined with mosapride in the treatment of senile functional constipation can improve their assist symptoms.