中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
33期
105-106
,共2页
益肾活血行水经验方%小剂量泼尼松%肾病综合征%肾功能%24 h尿蛋白定量
益腎活血行水經驗方%小劑量潑尼鬆%腎病綜閤徵%腎功能%24 h尿蛋白定量
익신활혈행수경험방%소제량발니송%신병종합정%신공능%24 h뇨단백정량
Yi Shen Huo Xue Xing Shui Jing Yan Fang%A small dose of prednisone%Nephrotic syndrome%Renal function%24h quantitative urinary protein
目的：观察益肾活血行水经验方内服联合小剂量泼尼松治疗肾病综合征的临床效果，并探讨其对患者尿蛋白定量、肾功能指标的影响。方法：收治肾病综合征患者76例，按照随机数字表法分为对照组和观察组各38例。对照组给予小剂量泼尼松治疗；观察组在此基础上给予益肾活血行水经验方内服治疗，1剂/d，15 d为1个疗程，治疗4个疗程。结果：经治疗后两组患者的24 h尿蛋白定量及肾功能各有关指标如尿β2微球蛋白(β2-MG)、尿白蛋白排泄率(UAER)水平、血肌酐(Scr)均较治疗前有所下降，但是以观察组变化幅度尤为明显(P＜0.05)；观察组有效率92.1%，对照组有效率68.4%，观察组的有效率明显高于对照组(P＜0.05)。结论：益肾活血行水经验方内服联合小剂量泼尼松能有效降低肾病综合征患者的24 h尿蛋白定量，改善患者的肾功能，效果满意，值得临床进一步推广运用。
目的：觀察益腎活血行水經驗方內服聯閤小劑量潑尼鬆治療腎病綜閤徵的臨床效果，併探討其對患者尿蛋白定量、腎功能指標的影響。方法：收治腎病綜閤徵患者76例，按照隨機數字錶法分為對照組和觀察組各38例。對照組給予小劑量潑尼鬆治療；觀察組在此基礎上給予益腎活血行水經驗方內服治療，1劑/d，15 d為1箇療程，治療4箇療程。結果：經治療後兩組患者的24 h尿蛋白定量及腎功能各有關指標如尿β2微毬蛋白(β2-MG)、尿白蛋白排洩率(UAER)水平、血肌酐(Scr)均較治療前有所下降，但是以觀察組變化幅度尤為明顯(P＜0.05)；觀察組有效率92.1%，對照組有效率68.4%，觀察組的有效率明顯高于對照組(P＜0.05)。結論：益腎活血行水經驗方內服聯閤小劑量潑尼鬆能有效降低腎病綜閤徵患者的24 h尿蛋白定量，改善患者的腎功能，效果滿意，值得臨床進一步推廣運用。
목적：관찰익신활혈행수경험방내복연합소제량발니송치료신병종합정적림상효과，병탐토기대환자뇨단백정량、신공능지표적영향。방법：수치신병종합정환자76례，안조수궤수자표법분위대조조화관찰조각38례。대조조급여소제량발니송치료；관찰조재차기출상급여익신활혈행수경험방내복치료，1제/d，15 d위1개료정，치료4개료정。결과：경치료후량조환자적24 h뇨단백정량급신공능각유관지표여뇨β2미구단백(β2-MG)、뇨백단백배설솔(UAER)수평、혈기항(Scr)균교치료전유소하강，단시이관찰조변화폭도우위명현(P＜0.05)；관찰조유효솔92.1%，대조조유효솔68.4%，관찰조적유효솔명현고우대조조(P＜0.05)。결론：익신활혈행수경험방내복연합소제량발니송능유효강저신병종합정환자적24 h뇨단백정량，개선환자적신공능，효과만의，치득림상진일보추엄운용。
Objective:To obeserve the clinical effect of Yi Shen Huo Xue Xing Shui Jing Yan Fang combined with small dose of prednisone in the treatment of nephrotic syndrome,and to explore the influence on the quantity of urinary protein and renal function index.Methods:76 patients with nephrotic syndrome were selected.According to the random number table method,they were divided into the observation group and the control group with 38 cases in each.The control group were treated with small dose of prednisone;the observation group were treated with Yi Shen Huo Xue Xing Shui Jing Yan Fang on the basis of the control group,1 agent/day.1 period of treatment was 15 days.All patients were treated for 4 courses of treatment.Results:After treatment, 24 h quantitative urinary protein and renal function indexes of the two groups,such as urinary β 2 microglobulin,urinary albumin excretion rate,creatinin were decreased,but in the observation group,it was more obvious(P<0.05).In the observation group,the efficiency was 92.1%;in the control group,efficiency was 68.4%;the observation group was significantly higher than the control group(P<0.05).Conclusion:Yi Shen Huo Xue Xing Shui Jing Yan Fang combined with small dose of prednisone can effectively reduce 24 h quantitative urinary protein in nephrotic syndrome,and improve renal function.The effect is satisfactory.It is worthy to be widely used.
