中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2014年
25期
36-37
,共2页
甲状旁腺素%血液透析%血液灌流%血液透析滤过
甲狀徬腺素%血液透析%血液灌流%血液透析濾過
갑상방선소%혈액투석%혈액관류%혈액투석려과
Parathyroid hormone%Hemodialysis%Hemoperfusion%Hemodiafiltration
目的：探讨不同血液净化方式对维持性血液透析患者甲状旁腺素（PTH）的影响。方法将该院维持性血液透析患者62例随机分成3组：即血液透析组（HD）10例，血液透析+血液灌流组（HD+HP）27例，血液透析+血液透析滤过组（HD+HDF）25例。各组均于治疗前及治疗12周后检测PTH水平。结果 HD组治疗前后PTH水平差异无统计学意义（P＝0.089，P＞0.05）；HD+HP组及HD+HDF组治疗前后PTH水平均有不同程度下降（P＝0.002，P＝0.005，均为P＜0.01），且HD+HP组比HD+HDF组PTH水平下降更为显著，差异有统计学意义（P＝0.012，P＜0.05）。结论 HD+HP及HD+HDF血液净化方式能有效降低维持性血液透析患者PTH水平，且HD+HP方式优于HD+HDF。
目的：探討不同血液淨化方式對維持性血液透析患者甲狀徬腺素（PTH）的影響。方法將該院維持性血液透析患者62例隨機分成3組：即血液透析組（HD）10例，血液透析+血液灌流組（HD+HP）27例，血液透析+血液透析濾過組（HD+HDF）25例。各組均于治療前及治療12週後檢測PTH水平。結果 HD組治療前後PTH水平差異無統計學意義（P＝0.089，P＞0.05）；HD+HP組及HD+HDF組治療前後PTH水平均有不同程度下降（P＝0.002，P＝0.005，均為P＜0.01），且HD+HP組比HD+HDF組PTH水平下降更為顯著，差異有統計學意義（P＝0.012，P＜0.05）。結論 HD+HP及HD+HDF血液淨化方式能有效降低維持性血液透析患者PTH水平，且HD+HP方式優于HD+HDF。
목적：탐토불동혈액정화방식대유지성혈액투석환자갑상방선소（PTH）적영향。방법장해원유지성혈액투석환자62례수궤분성3조：즉혈액투석조（HD）10례，혈액투석+혈액관류조（HD+HP）27례，혈액투석+혈액투석려과조（HD+HDF）25례。각조균우치료전급치료12주후검측PTH수평。결과 HD조치료전후PTH수평차이무통계학의의（P＝0.089，P＞0.05）；HD+HP조급HD+HDF조치료전후PTH수평균유불동정도하강（P＝0.002，P＝0.005，균위P＜0.01），차HD+HP조비HD+HDF조PTH수평하강경위현저，차이유통계학의의（P＝0.012，P＜0.05）。결론 HD+HP급HD+HDF혈액정화방식능유효강저유지성혈액투석환자PTH수평，차HD+HP방식우우HD+HDF。
Objective To explore the effect of different blood purification methods on the parathyroid hormone (PTH) of patients with maintenance hemodialysis. Methods 62 patients underwent maintenance hemodialysis in our hospital were randomly divided into 3 groups: hemodialysis(HD) group(n=10), hemodialysis +hemoperfusion(HD+HP) group(n=27), hemodialysis+hemodiafiltration (HD+HDF) group (n=25). The levels of PTH of the three groups of patients were detected before treatment and 12 weeks after treatment. Results There were no significant changes of PTH levels before and after treatment in group HD(P=0.089, P>0.05). PTH levels decreased before and after treatment with different degrees in group HD+HP and HD+HDF (P=0.002; P=0.005, all P<0.01), and PTH levels decreased more significantly in group HD+HP than in group HD+HDF(P=0.012, P<0.05). Conclusion HD+HP and HD+HDF blood purification methods can effectively reduce the PTH level of maintenance hemodialysis patients, and HD+HP is better than HD+HDF.
