CAJ | 학술논문

目的：探讨乌司他丁治疗脓毒症的疗效。方法：2012年7月-2013年7月收治脓毒症患者80例，随机分为对照组和试验组，对照组给予常规治疗，试验组在对照组的基础上联合乌司他丁治疗。比较两组患者的临床疗效。结果：治疗后，试验组的APACHE Ⅱ评分、Marsha Ⅱ评分改善情况明显优于对照组，差异有统计学意义(P＜0.05)。治疗后，试验组的 IL-6、TNF-α、Ny-proBNP水平明显比对照组低，差异有统计学意义(P＜0.05)。结论：乌司他丁治疗脓毒症患者疗效理想，安全可靠，值得普及和应用。
목적：탐토오사타정치료농독증적료효。방법：2012년7월-2013년7월수치농독증환자80례，수궤분위대조조화시험조，대조조급여상규치료，시험조재대조조적기출상연합오사타정치료。비교량조환자적림상료효。결과：치료후，시험조적APACHE Ⅱ평분、Marsha Ⅱ평분개선정황명현우우대조조，차이유통계학의의(P＜0.05)。치료후，시험조적 IL-6、TNF-α、Ny-proBNP수평명현비대조조저，차이유통계학의의(P＜0.05)。결론：오사타정치료농독증환자료효이상，안전가고，치득보급화응용。
Objective:To investigate the effect of ulinastatin in the treatment of sepsis.Methods: 80 patients with sepsis were selected from July 2012 to July 2013.They were randomly divided into the control group and the experimental group.The control group were given conventional therapy.The experimental group combined with ulinastatin on the basis of the control group.We compared the clinical efficacy of two groups.Results:After the treatment,the APACHE Ⅱ score,and Marsha Ⅱ score of the experimental group were significantly higher than those of the control group,and the difference was statistically significant(P<0.05).After the treatment,the IL-6,TNF-alpha,Ny-proBNP levels of the experimental group were significantly lower than those of the control group,and the difference was statistically significant(P<0.05).Conclusion:The effect of ulinastatin in treating patients with sepsis are safe and reliable,and it is worthy to be popularized and applied.