CAJ | 학술논문

目的：探讨儿童紫癜性肾炎临床分型与病理分级之间的关系。方法回顾性分析60例经肾活检确诊为紫癜性肾炎患儿的临床资料和病理特点。结果①临床分型中血尿和蛋白尿型37例（61.7%)最多，肾病综合征型16例（26.7%)次之；肾脏病理分级以Ⅱ、Ⅲ级最多。血尿和蛋白尿型病理分级以Ⅱ、Ⅲ级为主，肾病综合征型病理分级以Ⅲb级为主。②免疫病理分型以IgA+IgM沉积型最多（38.3%)，其次为IgA+IgM+IgG沉积型（35%)。结论临床表现严重的紫癜性肾炎患儿肾脏病理分级重，应早期肾活检，尽早制定治疗方案。
목적：탐토인동자전성신염림상분형여병리분급지간적관계。방법회고성분석60례경신활검학진위자전성신염환인적림상자료화병리특점。결과①림상분형중혈뇨화단백뇨형37례（61.7%)최다，신병종합정형16례（26.7%)차지；신장병리분급이Ⅱ、Ⅲ급최다。혈뇨화단백뇨형병리분급이Ⅱ、Ⅲ급위주，신병종합정형병리분급이Ⅲb급위주。②면역병리분형이IgA+IgM침적형최다（38.3%)，기차위IgA+IgM+IgG침적형（35%)。결론림상표현엄중적자전성신염환인신장병리분급중，응조기신활검，진조제정치료방안。
Objective To investigate the relationship between the clinical manifestation and pathological grading of Henoch-Schonlin purpura nephritis in children. Methods The clinical data and pathological characteristics of 60 children confirmedly diagnosed with Henoch-Schonlein purpura nephritis by renal biopsy were reviewed retrospectively. Results①The heamaturia and proteinuria (37 cases, 61.7%) were the most common clinical type, followed by nephrotic syndrome (16 cases, 26.7%). The major pathological type of HSPN were gradeⅡ and grade Ⅲ. The main pathological changes of heamaturia and proteinuria type were gradeⅡ and gradeⅢ, and the main pathological changes of nephrotic syndrome were gradeⅢb.② IgA+IgM deposit(38.3%) was the most com-mon immune pathological type, followed by IgA+IgM+IgG deposit (35%). Conclusion The more severe clinical manifestations in purpura nephritis children are, the more severe their renal pathology will be, so renal biopsy should be done and treatment plan should be made as early as possible.