CAJ | 학술논문

目的：评价关元穴-足三里联合针刺用于防治七氟醚肾损伤的安全性及有效性。方法随机选择全麻下行断指再植患者60例。采取随机双盲法分为两组,每组30例。 A组七氟醚-瑞芬太尼麻醉,辅以关元穴-足三里联合针刺组,B组七氟醚-瑞芬太尼麻醉组。观察记录两组患者麻醉前﹑术后即刻﹑麻醉后24 h﹑48 h的血清尿素氮﹑血肌酐情况,测定两组患者麻醉前﹑术后即刻﹑麻醉后24 h﹑48 h的超氧化物歧化酶﹑丙二醛情况。结果B组术后即刻﹑术后24 h﹑术后48 h血肌酐升高明显高于A组(P<0.05)；A组术后即刻﹑术后24 h﹑术后48 h超氧化物歧化酶浓度明显高于B组(P<0.05)。结论关元穴-足三里联合针刺用于防治七氟醚肾损伤安全性﹑有效。
목적：평개관원혈-족삼리연합침자용우방치칠불미신손상적안전성급유효성。방법수궤선택전마하행단지재식환자60례。채취수궤쌍맹법분위량조,매조30례。 A조칠불미-서분태니마취,보이관원혈-족삼리연합침자조,B조칠불미-서분태니마취조。관찰기록량조환자마취전﹑술후즉각﹑마취후24 h﹑48 h적혈청뇨소담﹑혈기항정황,측정량조환자마취전﹑술후즉각﹑마취후24 h﹑48 h적초양화물기화매﹑병이철정황。결과B조술후즉각﹑술후24 h﹑술후48 h혈기항승고명현고우A조(P<0.05)；A조술후즉각﹑술후24 h﹑술후48 h초양화물기화매농도명현고우B조(P<0.05)。결론관원혈-족삼리연합침자용우방치칠불미신손상안전성﹑유효。
Objective To evaluate the safety and effectiveness of Guanyuan combined with Zusanli acupuncture for the prevention and treatment of renal injury due to sevoflurane. Methods 60 cases underwent severed finger reunion under general anesthesia were randomly selected and divided into two groups according to the randomized double-blind method with 30 cases in each. Group A were given sevoflurane-remifentanil anesthesia, supplemented by Guanyuan combined with Zusanli acupuncture, and group B were given sevoflurane-remifentanil anesthesia. The serum urea nitrogen, serum creatinine before anesthesia, immediately after operation, 24 h, 48h after anesthesia of the two groups were observed and recorded. And the superoxide dismutase, malon-aldehyde were measured in the two groups before anesthesia, immediately after operation, 24 h, 48 h after anesthesia. Results The elevated serum creatinine levels of group B immediately after operation, 24 h and 48h after operation were obviously higher than those of group A (P<0.05);the superoxide dismutase concentration of group A immediately after operation, 24 h and 48h after op-eration were significantly higher than those of group B (P<0.05). Conclusion Guanyuan combined with Zusanli acupuncture is safe and effective in the prevention and treatment of renal injury due to sevoflurane.