中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
4期
112-113
,共2页
胃癌组织%癌旁组织%甘露糖结合凝集素(MBL)%相关丝氨酸蛋白酶2(MASP-2)%P53
胃癌組織%癌徬組織%甘露糖結閤凝集素(MBL)%相關絲氨痠蛋白酶2(MASP-2)%P53
위암조직%암방조직%감로당결합응집소(MBL)%상관사안산단백매2(MASP-2)%P53
Gastric cancer tissue%Para-carcinoma tissues%Mannose binding lectin(MBL)%Associated serine protease 2(MASP-2)%P53
目的：检测甘露糖结合凝集素(MBL)和相关的丝氨酸蛋白酶2(MASP-2)及P53在胃癌组织及癌旁组织的表达情况。方法：收治胃癌患者60例，应用免疫组织化学技术检测胃癌组织及癌旁组织中MBL和MASP-2及P53的表达情况。结果：在胃癌组织，MBL和MASP-2均表现为低表达，而在癌旁组织高表达，差异有统计学意义(χ2=6.00，P＜0.05)。P53主要在胃癌组织胞核中表达，P53阳性表达率51.66%(31/60)。结论：MBL和MASP-2在胃肿瘤及发生发展中表现了一定的作用。
目的：檢測甘露糖結閤凝集素(MBL)和相關的絲氨痠蛋白酶2(MASP-2)及P53在胃癌組織及癌徬組織的錶達情況。方法：收治胃癌患者60例，應用免疫組織化學技術檢測胃癌組織及癌徬組織中MBL和MASP-2及P53的錶達情況。結果：在胃癌組織，MBL和MASP-2均錶現為低錶達，而在癌徬組織高錶達，差異有統計學意義(χ2=6.00，P＜0.05)。P53主要在胃癌組織胞覈中錶達，P53暘性錶達率51.66%(31/60)。結論：MBL和MASP-2在胃腫瘤及髮生髮展中錶現瞭一定的作用。
목적：검측감로당결합응집소(MBL)화상관적사안산단백매2(MASP-2)급P53재위암조직급암방조직적표체정황。방법：수치위암환자60례，응용면역조직화학기술검측위암조직급암방조직중MBL화MASP-2급P53적표체정황。결과：재위암조직，MBL화MASP-2균표현위저표체，이재암방조직고표체，차이유통계학의의(χ2=6.00，P＜0.05)。P53주요재위암조직포핵중표체，P53양성표체솔51.66%(31/60)。결론：MBL화MASP-2재위종류급발생발전중표현료일정적작용。
Objective:To detect the expression of mannose binding lectin(MBL) and associated serine protease 2(MASP-2) and P53 in gastric carcinoma tissues and para-carcinoma tissues.Methods:60 patients with gastric cancer were selected.Immunohistochemis-try technique was applied to detect the expression of MBL and MASP-2 and P53 in gastric carcinoma tissues and para-carcinoma tissues.Results:In gastric cancer tissues,MBL and MASP-2 were low expression;in the adjacent tissues of cancer,they were high ex-pression;the difference was statistically significant(χ 2=6.00,P<0.05).P53 was mainly expressed in cell nucleus of gastric cancer tissues,and P53 positive expression rate was 51.66%(31/60).Conclusion:MBL and MASP-2 have a certain role in the occurrence and development of gastric cancer.
