中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
3期
36-37
,共2页
奥曲肽%给药方式%急性胰腺炎
奧麯肽%給藥方式%急性胰腺炎
오곡태%급약방식%급성이선염
Octreotide%Administered method%Acute pancreatitis
目的：探讨奥曲肽不同给药方式治疗急性胰腺炎的疗效差异，以指导临床选择最佳的治疗方案。方法：2012年2月-2014年7月收治急性胰腺炎患者60例，根据给药方法的不同随机分为微量注射泵持续注射组和皮下注射组，各30例，两组患者均按照平衡电解质、降低胃肠压、抑制胰酶活性的治疗原则进行治疗，皮下注射组在此基础上采用皮下注射奥曲肽0.1 mg/次，每6～8 h 1次，连续治疗7 d。微量注射泵持续注射组采用微量注射泵持续注射奥曲肽给药方式治疗，给药速率25μg/h，连续治疗7 d。结果：微量注射泵持续注射组症状消失时间、淀粉酶恢复时间、并发症发生情况和住院天数方面明显低于皮下注射组，差异有统计学意义(P＜0.05)，微量注射泵持续注射组痊愈17例，有效11例，无效2例，总有效率93.3%；皮下注射组痊愈13例，有效10例，无效7例，总有效率76.7%，两组差异有统计学意义。
目的：探討奧麯肽不同給藥方式治療急性胰腺炎的療效差異，以指導臨床選擇最佳的治療方案。方法：2012年2月-2014年7月收治急性胰腺炎患者60例，根據給藥方法的不同隨機分為微量註射泵持續註射組和皮下註射組，各30例，兩組患者均按照平衡電解質、降低胃腸壓、抑製胰酶活性的治療原則進行治療，皮下註射組在此基礎上採用皮下註射奧麯肽0.1 mg/次，每6～8 h 1次，連續治療7 d。微量註射泵持續註射組採用微量註射泵持續註射奧麯肽給藥方式治療，給藥速率25μg/h，連續治療7 d。結果：微量註射泵持續註射組癥狀消失時間、澱粉酶恢複時間、併髮癥髮生情況和住院天數方麵明顯低于皮下註射組，差異有統計學意義(P＜0.05)，微量註射泵持續註射組痊愈17例，有效11例，無效2例，總有效率93.3%；皮下註射組痊愈13例，有效10例，無效7例，總有效率76.7%，兩組差異有統計學意義。
목적：탐토오곡태불동급약방식치료급성이선염적료효차이，이지도림상선택최가적치료방안。방법：2012년2월-2014년7월수치급성이선염환자60례，근거급약방법적불동수궤분위미량주사빙지속주사조화피하주사조，각30례，량조환자균안조평형전해질、강저위장압、억제이매활성적치료원칙진행치료，피하주사조재차기출상채용피하주사오곡태0.1 mg/차，매6～8 h 1차，련속치료7 d。미량주사빙지속주사조채용미량주사빙지속주사오곡태급약방식치료，급약속솔25μg/h，련속치료7 d。결과：미량주사빙지속주사조증상소실시간、정분매회복시간、병발증발생정황화주원천수방면명현저우피하주사조，차이유통계학의의(P＜0.05)，미량주사빙지속주사조전유17례，유효11례，무효2례，총유효솔93.3%；피하주사조전유13례，유효10례，무효7례，총유효솔76.7%，량조차이유통계학의의。
Objective:To explore the curative effect differences of different administration methods of octreotide in the treatment of acute pancreatitis,to guide the clinical selection of the best therapeutic scheme.Methods:60 patients with acute pancreatitis were selected from February 2012 to July 2014.According to the different administration methods,they were randomly divided into the trace injection pump continuous injection group and the subcutaneous injection group with 30 cases in each.According to the balance of electrolyte,reducing gastrointestinal pressure,inhibition of pancreatic enzymes treatment principle,the patients in two groups were given treatment.On this basis,the control group were given subcutaneous injection of octreotide 0.1 mg one time,1 time 6~8 hours,continuous treatment of 7days.The trace injection pump continuous injection group were given trace injection pump continuous injection of octreotide administered treatment,dosing rate was 25 μg one hour,continuous treatment of 7 days. Results:The symptoms disappear time, amylase recovery time,complications and hospitalization days of the trace injection pump continuous injection group were significantly lower than those of the subcutaneous injection group,and the difference was statistically significant(P<0.05).In the trace injection pump continuous injection group,17 cases were cured; 11 cases were effective;2 cases were invalid;the total effective rate was 93.3%.In the subcutaneous injection group,13 cases were cured;10 cases were effective;7 cases were invalid;the total effective rate was 76.7% ,and the difference was statistically significant(P<0.05). Conclusion:The trace injection pump continuous injection of octreotide administered treatment has significant treatment effect,so it is worthy of promotion.
