CAJ | 학술논문

目的：分析肝硬化患者并发自发性细菌性腹膜炎腹水病原菌及耐药性。方法：2013年1月-2014年1月收治肝硬化并发自发性细菌性腹膜炎患者50例，进行腹水细菌培养。结果：腹水细菌培养后，发现其均为单一菌种，并且革兰阴性杆菌35例(70%)。病原菌的耐药性分析：革兰阴性杆菌中第三代头孢菌素的耐药率明显要好于第四代头孢菌素，并且氨节西林的耐药率最高。结论：根据肝硬化患者并发自发性细菌性腹膜炎腹水病原菌及耐药性分析结果选择相应的治疗方法，不仅可以延缓细菌耐药性的产生，而且还能提高患者的临床治疗效果。
목적：분석간경화환자병발자발성세균성복막염복수병원균급내약성。방법：2013년1월-2014년1월수치간경화병발자발성세균성복막염환자50례，진행복수세균배양。결과：복수세균배양후，발현기균위단일균충，병차혁란음성간균35례(70%)。병원균적내약성분석：혁란음성간균중제삼대두포균소적내약솔명현요호우제사대두포균소，병차안절서림적내약솔최고。결론：근거간경화환자병발자발성세균성복막염복수병원균급내약성분석결과선택상응적치료방법，불부가이연완세균내약성적산생，이차환능제고환자적림상치료효과。
Objective:To analyze the ascites pathogenic bacteria and drug resistance of liver cirrhosis patients combined with spontaneous bacterial peritonitis.Methods:50 liver cirrhosis patients combined with spontaneous bacterial peritonitis were selected from January 2013 to January 2014.They were given ascites bacteria culture.Results:After ascites bacteria culture,it found that they all were single strain,and 35 cases(70% ) were gram-negative bacillus.Analysis of the drug resistance of pathogenic bacteria:the drug resistance of third generation cephalosporins in gram-negative bacillus was significantly better than that of the fourth generation cephalosporins,and the drug resistance of ampicillin was the highest.Conclusion:According to the ascites pathogenic bacteria and drug resistance analysis results of liver cirrhosis patients combined with spontaneous bacterial peritonitis,selecting the appropriate treatment not only can delay the production of drug resistance,but also can improve the clinical treatment effect of patients.