现代中西医结合杂志
現代中西醫結閤雜誌
현대중서의결합잡지
MODERN JOURNAL OF INTEGRATED TRADITIONAL CHINESE AND WESTERN MEDICINE
2009年
19期
2229-2232
,共4页
常富业%袁英%李云%李长新%原向芝%万继峰%李云超%孙莹%宋昕%赖杰%贾丽华%胡秋莹%陈燕
常富業%袁英%李雲%李長新%原嚮芝%萬繼峰%李雲超%孫瑩%宋昕%賴傑%賈麗華%鬍鞦瑩%陳燕
상부업%원영%리운%리장신%원향지%만계봉%리운초%손형%송흔%뢰걸%가려화%호추형%진연
脑卒中%二级预防%鸡尾酒疗法
腦卒中%二級預防%鷄尾酒療法
뇌졸중%이급예방%계미주요법
cerebral apoplexy%secondary preventive measure%cocktail therapy
目的 研究70岁以上缺血性脑梗死患者服用阿司匹林后脑梗死再发的相关因素.方法 采用随机、平行对照的方法 ,将既往已发脑梗死患者分为脑梗死再发组和脑梗死未再发组.观察研究时间窗内一般自身因素、生活方式、疾病相关因素及实验室检查指标的变化,探讨高龄患者服用阿司匹林后脑梗死再发的原因.结果 2组患者在体型、职业性质、饮酒方面无明显差异.在饮食结构、生活规律、睡眠质量、吸烟、锻炼、性格、就医、家族史和合并病等方面存在明显差异(P均<O.05).2组患者在高敏C反应蛋白(hs-CRP)、血脂、纤维蛋白原(Fg)、同型半胱氨酸(Hcy)等方面均有明显差异(P均<0.05),而在Plt、红细胞压积方面无明显差异.结论70岁以上缺血性脑梗死患者服用阿司匹林后脑梗死再发的原因是多方面的.除了与个体的一般自身因素、生活方式和疾病相关因素有关外,hs-CRP、血脂、Fg、Hcy等众多指标的多因素变化可能起重要作用.脑梗死的二级预防应该整合多种发病因素,实施预防个体化、综合化,切不可以偏概全.
目的 研究70歲以上缺血性腦梗死患者服用阿司匹林後腦梗死再髮的相關因素.方法 採用隨機、平行對照的方法 ,將既往已髮腦梗死患者分為腦梗死再髮組和腦梗死未再髮組.觀察研究時間窗內一般自身因素、生活方式、疾病相關因素及實驗室檢查指標的變化,探討高齡患者服用阿司匹林後腦梗死再髮的原因.結果 2組患者在體型、職業性質、飲酒方麵無明顯差異.在飲食結構、生活規律、睡眠質量、吸煙、鍛煉、性格、就醫、傢族史和閤併病等方麵存在明顯差異(P均<O.05).2組患者在高敏C反應蛋白(hs-CRP)、血脂、纖維蛋白原(Fg)、同型半胱氨痠(Hcy)等方麵均有明顯差異(P均<0.05),而在Plt、紅細胞壓積方麵無明顯差異.結論70歲以上缺血性腦梗死患者服用阿司匹林後腦梗死再髮的原因是多方麵的.除瞭與箇體的一般自身因素、生活方式和疾病相關因素有關外,hs-CRP、血脂、Fg、Hcy等衆多指標的多因素變化可能起重要作用.腦梗死的二級預防應該整閤多種髮病因素,實施預防箇體化、綜閤化,切不可以偏概全.
목적 연구70세이상결혈성뇌경사환자복용아사필림후뇌경사재발적상관인소.방법 채용수궤、평행대조적방법 ,장기왕이발뇌경사환자분위뇌경사재발조화뇌경사미재발조.관찰연구시간창내일반자신인소、생활방식、질병상관인소급실험실검사지표적변화,탐토고령환자복용아사필림후뇌경사재발적원인.결과 2조환자재체형、직업성질、음주방면무명현차이.재음식결구、생활규률、수면질량、흡연、단련、성격、취의、가족사화합병병등방면존재명현차이(P균<O.05).2조환자재고민C반응단백(hs-CRP)、혈지、섬유단백원(Fg)、동형반광안산(Hcy)등방면균유명현차이(P균<0.05),이재Plt、홍세포압적방면무명현차이.결론70세이상결혈성뇌경사환자복용아사필림후뇌경사재발적원인시다방면적.제료여개체적일반자신인소、생활방식화질병상관인소유관외,hs-CRP、혈지、Fg、Hcy등음다지표적다인소변화가능기중요작용.뇌경사적이급예방응해정합다충발병인소,실시예방개체화、종합화,절불가이편개전.
Objective It is to explore the factors related to the recurrence cause of cerebral infarction attacking in patients above 75 years old with ischemic cerebral infarction after taking aspirin. Methods The patients who had suffered from cere-bral infarction were randomly divided into recurrent group and non-recurrent group with the methods of random selection and parallel contrast. The general auto-factors, living style, factors related to the disease and changes of indexes of lab tests were observed to explore the cause of the recurrence of cerebral infarction attacking senior patients after taking aspirin. Results There were no significant differences between the two groups in body type, career and drinking alcohol, but there was dis-tinct differences (P < 0.05) in dietary structure, living pattern, sleeping quality, smoking, exercising personality, seeking medical advice, family history and complication etc. In the lab tests, there were distinct differences in hs- CRP, blood fat, Fg and Hey( P < 0.05), but no difference in Pit and HCT. Conclusion There are many factors leading to the recurrence of cerebral infarction attacking ischemic cerebral infarction patients above 70 years old after taking aspirin. Besides being related to the general auto-factors, living style, factors related to the disease, the recurrence is likely to be caused by the changes of indexes of hs- CRP, blood fat, Fg and Hey. The cocktail therapy is put forward to prevent cerebral apoplexy. The sec-ondary preventive measures of cerebral infarction should consider pathogenic factors in many ways. Treat patients individually and comprehensively. Don't take a one-sided approach to the disease.
